Integrated Genomics Identifies miR-32/MCL-1 Pathway as a Critical Driver of Melanomagenesis: Implications for miR-Replacement and Combination Therapy.

by Prasun J Mishra, Pravin J Mishra, Glenn Merlino
Published 2016-01-01

Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF.

by Rosaura Esteve-Puig, Francesc Canals, Núria Colomé, Glenn Merlino, Juan Angel Recio
Published 2009-01-01

PERK mediates resistance to BRAF inhibition in melanoma with impaired PTEN

by Yifei Qin, Qiang Zuo, Lei Huang, Liping Huang, Glenn Merlino, Yanlin Yu
Published 2021-07-01

Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene.

by Yanlin Yu, Pingyao Zeng, Jingbo Xiong, Ziyang Liu, Shelley L Berger, Glenn Merlino
Published 2010-09-01

Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intrader...

by Ashley Tarasen, J. Andrew Carlson, M. Kathryn Leonard, Glenn Merlino, David Kaetzel, Andrzej T. Slominski
Published 2017-08-01

Naturally Occurring Canine Melanoma as a Predictive Comparative Oncology Model for Human Mucosal and Other Triple Wild-Type Melanomas

by Belen Hernandez, Hibret A. Adissu, Bih-Rong Wei, Helen T. Michael, Glenn Merlino, R. Mark Simpson
Published 2018-01-01

Corrigendum to “Molecular profile of clonal strains of human skeletal stem/progenitor cells with different potencies” [stem cell res. 14 (2015) 297–306]

by Brian J. Sworder, Sayuri Yoshizawa, Prasun J. Mishra, Natasha Cherman, Sergei A. Kuznetsov, Glenn Merlino, Arun Balakumaran, Pamela G. Robey
Published 2015-07-01

Molecular profile of clonal strains of human skeletal stem/progenitor cells with different potencies

by Brian J. Sworder, Sayuri Yoshizawa, Prasun J. Mishra, Natasha Cherman, Sergei A. Kuznetsov, Glenn Merlino, Arun Balakumaran, Pamela G. Robey
Published 2015-05-01

MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism.

by Prasun J Mishra, Bo Song, Pravin J Mishra, Yuan Wang, Rita Humeniuk, Debabrata Banerjee, Glenn Merlino, Jingfang Ju, Joseph R Bertino
Published 2009-12-01

"Glowing head" mice: a genetic tool enabling reliable preclinical image-based evaluation of cancers in immunocompetent allografts.

by Chi-Ping Day, John Carter, Zoe Weaver Ohler, Carrie Bonomi, Rajaa El Meskini, Philip Martin, Cari Graff-Cherry, Lionel Feigenbaum, Thomas Tüting, Terry Van Dyke, Melinda Hollingshead, Glenn Merlino
Published 2014-01-01

Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα.

by Mohamed E Moustafa, Bradley A Carlson, Miriam R Anver, Gerd Bobe, Nianxin Zhong, Jerrold M Ward, Christine M Perella, Victoria J Hoffmann, Keith Rogers, Gerald F Combs, Ulrich Schweizer, Glenn Merlino, Vadim N Gladyshev, Dolph L Hatfield
Published 2013-01-01

A direct link between MITF, innate immunity, and hair graying.

by Melissa L Harris, Temesgen D Fufa, Joseph W Palmer, Sandeep S Joshi, Denise M Larson, Arturo Incao, Derek E Gildea, Niraj S Trivedi, Autumne N Lee, Chi-Ping Day, Helen T Michael, Thomas J Hornyak, Glenn Merlino, NISC Comparative Sequencing Program, William J Pavan
Published 2018-05-01

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.

by Olga Shakhova, Phil Cheng, Pravin J Mishra, Daniel Zingg, Simon M Schaefer, Julien Debbache, Jessica Häusel, Claudia Matter, Theresa Guo, Sean Davis, Paul Meltzer, Daniela Mihic-Probst, Holger Moch, Michael Wegner, Glenn Merlino, Mitchell P Levesque, Reinhard Dummer, Raffaella Santoro, Paolo Cinelli, Lukas Sommer
Published 2015-01-01

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

by Kerrie L. Marie, Antonella Sassano, Howard H. Yang, Aleksandra M. Michalowski, Helen T. Michael, Theresa Guo, Yien Che Tsai, Allan M. Weissman, Maxwell P. Lee, Lisa M. Jenkins, M. Raza Zaidi, Eva Pérez-Guijarro, Chi-Ping Day, Kris Ylaya, Stephen M. Hewitt, Nimit L. Patel, Heinz Arnheiter, Sean Davis, Paul S. Meltzer, Glenn Merlino, Pravin J. Mishra
Published 2020-01-01

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice

by Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Published 2019-04-01