The Amazing World of IDPs in Human Diseases

by Simona Maria Monti, Giuseppina De Simone, Emma Langella
Published 2021-02-01

Human carbonic anhydrases and post-translational modifications: a hidden world possibly affecting protein properties and functions

by Anna Di Fiore, Claudiu T. Supuran, Andrea Scaloni, Giuseppina De Simone
Published 2020-01-01

Cadmium-Containing Carbonic Anhydrase CDCA1 in Marine Diatom Thalassiosira weissflogii

by Vincenzo Alterio, Emma Langella, Giuseppina De Simone, Simona Maria Monti
Published 2015-03-01

Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibit...

by Vincenzo Alterio, Davide Esposito, Simona Maria Monti, Claudiu T. Supuran, Giuseppina De Simone
Published 2018-01-01

Thermostable Carbonic Anhydrases in Biotechnological Applications

by Anna Di Fiore, Vincenzo Alterio, Simona M. Monti, Giuseppina De Simone, Katia D'Ambrosio
Published 2015-07-01

Protective Role of Carbonic Anhydrases III and VII in Cellular Defense Mechanisms upon Redox Unbalance

by Anna Di Fiore, Daria M. Monti, Andrea Scaloni, Giuseppina De Simone, Simona M. Monti
Published 2018-01-01

Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage

by Daria M. Monti, Giuseppina De Simone, Emma Langella, Claudiu T. Supuran, Anna Di Fiore, Simona M. Monti
Published 2017-01-01

Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach

by Giuseppina De Simone, Anna Di Fiore, Emanuela Truppo, Emma Langella, Daniela Vullo, Claudiu T. Supuran, Simona Maria Monti
Published 2019-01-01

Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations

by Giuseppina De Simone, Emma Langella, Davide Esposito, Claudiu T. Supuran, Simona Maria Monti, Jean-Yves Winum, Vincenzo Alterio
Published 2017-01-01

Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides

by Linda J. Urbański, Andrea Angeli, Vesa P. Hytönen, Anna Di Fiore, Giuseppina De Simone, Seppo Parkkila, Claudiu T. Supuran
Published 2021-01-01

The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior

by Martina Buonanno, Anna Di Fiore, Emma Langella, Katia D’Ambrosio, Claudiu T. Supuran, Simona Maria Monti, Giuseppina De Simone
Published 2018-05-01

A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity

by Annachiara Sarnella, Giuliana D’Avino, Billy Samuel Hill, Vincenzo Alterio, Jean-Yves Winum, Claudiu T. Supuran, Giuseppina De Simone, Antonella Zannetti
Published 2020-11-01

Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme...

by Emma Langella, Vincenzo Alterio, Katia D’Ambrosio, Roberta Cadoni, Jean-Yves Winum, Claudiu T. Supuran, Simona Maria Monti, Giuseppina De Simone, Anna Di Fiore
Published 2019-01-01

Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors

by Giuseppina De Simone, Ginta Pizika, Simona Maria Monti, Anna Di Fiore, Jekaterina Ivanova, Igor Vozny, Peteris Trapencieris, Raivis Zalubovskis, Claudiu T. Supuran, Vincenzo Alterio
Published 2014-01-01

Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?

by Vincenzo Alterio, Emma Langella, Martina Buonanno, Davide Esposito, Alessio Nocentini, Emanuela Berrino, Silvia Bua, Maurizio Polentarutti, Claudiu T. Supuran, Simona Maria Monti, Giuseppina De Simone
Published 2021-01-01

Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis

by Linda J. Urbański, Anna Di Fiore, Latifeh Azizi, Vesa P. Hytönen, Marianne Kuuslahti, Martina Buonanno, Simona M. Monti, Andrea Angeli, Reza Zolfaghari Emameh, Claudiu T. Supuran, Giuseppina De Simone, Seppo Parkkila
Published 2020-01-01

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

by Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar, Claudiu T. Supuran
Published 2020-10-01