The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.

by Girish C Melkani, Rolf Bodmer, Karen Ocorr, Sanford I Bernstein
Published 2011-01-01

Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart.

by Girish C Melkani, Adriana S Trujillo, Raul Ramos, Rolf Bodmer, Sanford I Bernstein, Karen Ocorr
Published 2013-01-01

Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption

by Jesús E. Villanueva, Christopher Livelo, Adriana S. Trujillo, Sahaana Chandran, Brendon Woodworth, Leo Andrade, Hiep D. Le, Uri Manor, Satchidananda Panda, Girish C. Melkani
Published 2019-06-01

A Drosophila model of dominant inclusion body myopathy type 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects

by Jennifer A. Suggs, Girish C. Melkani, Bernadette M. Glasheen, Mia M. Detor, Anju Melkani, Nathan P. Marsan, Douglas M. Swank, Sanford I. Bernstein
Published 2017-06-01

Author Correction: Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption

by Jesús E. Villanueva, Christopher Livelo, Adriana S. Trujillo, Sahaana Chandran, Brendon Woodworth, Leo Andrade, Hiep D. Le, Uri Manor, Satchidananda Panda, Girish C. Melkani
Published 2020-05-01

Prolonged cross-bridge binding triggers muscle dysfunction in a Drosophila model of myosin-based hypertrophic cardiomyopathy

by William A Kronert, Kaylyn M Bell, Meera C Viswanathan, Girish C Melkani, Adriana S Trujillo, Alice Huang, Anju Melkani, Anthony Cammarato, Douglas M Swank, Sanford I Bernstein
Published 2018-08-01