A Galantamine–Curcumin Hybrid Decreases the Cytotoxicity of Amyloid-Beta Peptide on SH-SY5Y Cells

by Kirilka Mladenova, Georgi Stavrakov, Irena Philipova, Mariyana Atanasova, Svetla Petrova, Jordan Doumanov, Irini Doytchinova
Published 2021-07-01

A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders

by Rumyana Simeonova, Dimitrina Zheleva, Iva Valkova, Georgi Stavrakov, Irena Philipova, Mariyana Atanasova, Irini Doytchinova
Published 2021-03-01

Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening

by Georgi Stavrakov, Irena Philipova, Atanas Lukarski, Mariyana Atanasova, Borislav Georgiev, Teodora Atanasova, Spiro Konstantinov, Irini Doytchinova
Published 2021-04-01

Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database

by Irini Doytchinova, Mariyana Atanasova, Iva Valkova, Georgi Stavrakov, Irena Philipova, Zvetanka Zhivkova, Dimitrina Zheleva-Dimitrova, Spiro Konstantinov, Ivan Dimitrov
Published 2018-01-01

Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors

by Georgi Stavrakov, Irena Philipova, Atanas Lukarski, Mariyana Atanasova, Dimitrina Zheleva, Zvetanka D. Zhivkova, Stefan Ivanov, Teodora Atanasova, Spiro Konstantinov, Irini Doytchinova
Published 2020-07-01