Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

by George D. Cresswell, Daniel Nichol, Inmaculada Spiteri, Haider Tari, Luis Zapata, Timon Heide, Carlo C. Maley, Luca Magnani, Gaia Schiavon, Alan Ashworth, Peter Barry, Andrea Sottoriva
Published 2020-03-01

Somatic TP53 Mutations Are Detectable in Circulating Tumor DNA from Children with Anaplastic Wilms Tumors

by Taryn D. Treger, Tasnim Chagtai, Robert Butcher, George D. Cresswell, Reem Al-Saadi, Jesper Brok, Richard D. Williams, Chrissy Roberts, Nicholas M. Luscombe, Kathy Pritchard Jones, William Mifsud
Published 2018-12-01

Measuring single cell divisions in human tissues from multi-region sequencing data

by Benjamin Werner, Jack Case, Marc J. Williams, Ketevan Chkhaidze, Daniel Temko, Javier Fernández-Mateos, George D. Cresswell, Daniel Nichol, William Cross, Inmaculada Spiteri, Weini Huang, Ian P. M. Tomlinson, Chris P. Barnes, Trevor A. Graham, Andrea Sottoriva
Published 2020-02-01

Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications

by George D. Cresswell, John R. Apps, Tasnim Chagtai, Borbala Mifsud, Christopher C. Bentley, Mariana Maschietto, Sergey D. Popov, Mark E. Weeks, Øystein E. Olsen, Neil J. Sebire, Kathy Pritchard-Jones, Nicholas M. Luscombe, Richard D. Williams, William Mifsud
Published 2016-07-01

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

by Ahmet Acar, Daniel Nichol, Javier Fernandez-Mateos, George D. Cresswell, Iros Barozzi, Sung Pil Hong, Nicholas Trahearn, Inmaculada Spiteri, Mark Stubbs, Rosemary Burke, Adam Stewart, Giulio Caravagna, Benjamin Werner, Georgios Vlachogiannis, Carlo C. Maley, Luca Magnani, Nicola Valeri, Udai Banerji, Andrea Sottoriva
Published 2020-04-01