Phase I/II Clinical Trials Using Gene-Modified Adult Hematopoietic Stem Cells for HIV: Lessons Learnt

by Ronald T. Mitsuyasu, Jerome A. Zack, Janet L. Macpherson, Geoff P. Symonds
Published 2011-01-01

CCR5 as a Natural and Modulated Target for Inhibition of HIV

by Bryan P. Burke, Maureen P. Boyd, Helen Impey, Louis R. Breton, Jeffrey S. Bartlett, Geoff P. Symonds, Gero Hütter
Published 2013-12-01

The feasibility of incorporating Vpx into lentiviral gene therapy vectors

by Samantha A McAllery, Chantelle L Ahlenstiel, Kazuo Suzuki, Geoff P Symonds, Anthony D Kelleher, Stuart G Turville
Published 2016-01-01

Controlling HIV-1: Non-coding RNA gene therapy approaches to a functional cure

by Chantelle L Ahlenstiel, Kazuo eSuzuki, Kazuo eSuzuki, Katherine eMarks, Geoff P Symonds, Anthony D Kelleher, Anthony D Kelleher
Published 2015-09-01

Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS

by Christopher W. Peterson, Kevin G. Haworth, Bryan P. Burke, Patricia Polacino, Krystin K. Norman, Jennifer E. Adair, Shiu-Lok Hu, Jeffrey S. Bartlett, Geoff P. Symonds, Hans-Peter Kiem
Published 2016-01-01

Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.

by Gene-Errol E Ringpis, Saki Shimizu, Hubert Arokium, Joanna Camba-Colón, Maria V Carroll, Ruth Cortado, Yiming Xie, Patrick Y Kim, Anna Sahakyan, Emily L Lowe, Munetoshi Narukawa, Fadi N Kandarian, Bryan P Burke, Geoff P Symonds, Dong Sung An, Irvin S Y Chen, Masakazu Kamata
Published 2012-01-01

Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor

by Orit Wolstein, Maureen Boyd, Michelle Millington, Helen Impey, Joshua Boyer, Annett Howe, Frederic Delebecque, Kenneth Cornetta, Michael Rothe, Christopher Baum, Tamara Nicolson, Rachel Koldej, Jane Zhang, Naomi Keech, Joanna Camba Colón, Louis Breton, Jeffrey Bartlett, Dong Sung An, Irvin SY Chen, Bryan Burke, Geoff P Symonds
Published 2014-01-01

Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector

by Bryan P Burke, Bernard R Levin, Jane Zhang, Anna Sahakyan, Joshua Boyer, Maria V Carroll, Joanna Camba Colón, Naomi Keech, Valerie Rezek, Gregory Bristol, Erica Eggers, Ruth Cortado, Maureen P Boyd, Helen Impey, Saki Shimizu, Emily L Lowe, Gene-Errol E Ringpis, Sohn G Kim, Dimitrios N Vatakis, Louis R Breton, Jeffrey S Bartlett, Irvin S Y Chen, Scott G Kitchen, Dong Sung An, Geoff P Symonds
Published 2015-01-01