Article Dosimetry Inter-cyclic changes Neuroblastoma Peptide receptor radionuclide therapy Pharmacokinetics [177Lu]Lu-DOTATATE body weight child clinical article controlled study dose response dosimetry drug absorption drug clearance drug dose escalation drug dose regimen drug tumor level drug uptake female follow up human kidney liver male multiple cycle treatment neuroblastoma organs at risk oxodotreotide lutetium lu 177 pharmacokinetic assay