A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus.

by Rebecca A Owens, Stephen Hammel, Kevin J Sheridan, Gary W Jones, Sean Doyle
Published 2014-01-01

Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity

by Elizabeth B. Smith, Stephen K. Dolan, David A. Fitzpatrick, Sean Doyle, Gary W. Jones
Published 2016-02-01

The roles of whole-genome and small-scale duplications in the functional specialization of Saccharomyces cerevisiae genes.

by Mario A Fares, Orla M Keane, Christina Toft, Lorenzo Carretero-Paulet, Gary W Jones
Published 2013-01-01

Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus

by Stephen K. Dolan, Tobias Bock, Vanessa Hering, Rebecca A. Owens, Gary W. Jones, Wulf Blankenfeldt, Sean Doyle
Published 2017-01-01

Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic Implications

by Aimee M. Traynor, Kevin J. Sheridan, Gary W. Jones, José A. Calera, José A. Calera, Sean Doyle
Published 2019-12-01

Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation.

by Linan Xu, Naushaba Hasin, Manli Shen, Jianwei He, Youlin Xue, Xiaohong Zhou, Sarah Perrett, Youtao Song, Gary W Jones
Published 2013-01-01

Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin.

by Markus Schrettl, Stephen Carberry, Kevin Kavanagh, Hubertus Haas, Gary W Jones, Jennifer O'Brien, Aine Nolan, John Stephens, Orla Fenelon, Sean Doyle
Published 2010-06-01

Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes.

by David A Fitzpatrick, Jennifer O'Brien, Ciara Moran, Naushaba Hasin, Elaine Kenny, Paul Cormican, Amy Gates, Derek W Morris, Gary W Jones
Published 2011-01-01