A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model

by Timothy W. Phares, Vinayaka Kotraiah, Deshapriya S. Karunarathne, Jing Huang, Cecille D. Browne, Peter Buontempo, Marc Mansour, Amy R. Noe, Michelle N. Wykes, James Pannucci, Moriya Tsuji, Gabriel M. Gutierrez
Published 2020-07-01

Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

by Kenneth D. Tucker, Brian C. Schanen, Timothy W. Phares, Emily Sassano, Frances E. Terry, Pooja Hindocha, Leonard Moise, Vinayaka Kotraiah, William D. Martin, Anne S. De Groot, Anne S. De Groot, Donald R. Drake, Gabriel M. Gutierrez, Amy R. Noe
Published 2021-05-01

Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization

by Vinayaka Kotraiah, Timothy W. Phares, Frances E. Terry, Pooja Hindocha, Sarah E. Silk, Carolyn M. Nielsen, Leonard Moise, Kenneth D. Tucker, Rebecca Ashfield, William D. Martin, Anne S. De Groot, Anne S. De Groot, Simon J. Draper, Gabriel M. Gutierrez, Amy R. Noe
Published 2021-07-01

Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein...

by Amy R. Noe, Frances E. Terry, Brian C. Schanen, Emily Sassano, Pooja Hindocha, Timothy W. Phares, Leonard Moise, Jayne M. Christen, Kenneth D. Tucker, Vinayaka Kotraiah, Donald R. Drake, William D. Martin, Anne S. De Groot, Anne S. De Groot, Gabriel M. Gutierrez
Published 2021-06-01

Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

by Vinayaka Kotraiah, Timothy W. Phares, Cecille D. Browne, James Pannucci, Marc Mansour, Amy R. Noe, Kenneth D. Tucker, Jayne M. Christen, Charles Reed, Alecia MacKay, Genevieve M. Weir, Rajkannan Rajagopalan, Marianne M. Stanford, Chun-Shiang Chung, Alfred Ayala, Jing Huang, Moriya Tsuji, Gabriel M. Gutierrez
Published 2020-03-01

A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidate.

by Amy R Noe, Diego Espinosa, Xiangming Li, Jordana G A Coelho-Dos-Reis, Ryota Funakoshi, Steve Giardina, Hongfan Jin, Diane M Retallack, Ryan Haverstock, Jeffrey R Allen, Thomas S Vedvick, Christopher B Fox, Steven G Reed, Ramses Ayala, Brian Roberts, Scott B Winram, John Sacci, Moriya Tsuji, Fidel Zavala, Gabriel M Gutierrez
Published 2014-01-01