microRNA Therapeutics in Cancer — An Emerging Concept

by Maitri Y. Shah, Alessandra Ferrajoli, Anil K Sood, Gabriel Lopez-Berestein, George A. Calin
Published 2016-10-01

Explainable Artificial Intelligence Reveals Novel Insight into Tumor Microenvironment Conditions Linked with Better Prognosis in Patients with Breast Cancer

by Debaditya Chakraborty, Cristina Ivan, Paola Amero, Maliha Khan, Cristian Rodriguez-Aguayo, Hakan Başağaoğlu, Gabriel Lopez-Berestein
Published 2021-07-01

Back to the Future: Rethinking the Great Potential of lncRNA_S for Optimizing Chemotherapeutic Response in Ovarian Cancer

by Abdelrahman M. Elsayed, Paola Amero, Salama A. Salama, Abdelaziz H. Abdelaziz, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo
Published 2020-08-01

The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironment.

by Vijaya Ramachandran, Thiruvengadam Arumugam, Robert Langley, Rosa F Hwang, Pablo Vivas-Mejia, Anil K Sood, Gabriel Lopez-Berestein, Craig D Logsdon
Published 2009-10-01

Blockade of CDK7 Reverses Endocrine Therapy Resistance in Breast Cancer

by Yasmin M. Attia, Samia A. Shouman, Salama A. Salama, Cristina Ivan, Abdelrahman M. Elsayed, Paola Amero, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein
Published 2020-04-01

Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Ort...

by Ibrahim Tekedereli, S Neslihan Alpay, Ugur Akar, Erkan Yuca, Cristian Ayugo-Rodriguez, He-Dong Han, Anil K Sood, Gabriel Lopez-Berestein, Bulent Ozpolat
Published 2013-01-01

Enhancing chemotherapy response with Bmi-1 silencing in ovarian cancer.

by Enfeng Wang, Sanjib Bhattacharyya, Annamaria Szabolcs, Cristian Rodriguez-Aguayo, Nicholas B Jennings, Gabriel Lopez-Berestein, Priyabrata Mukherjee, Anil K Sood, Resham Bhattacharya
Published 2011-03-01

miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas

by Jill H. Tseng, Maria Bisogna, Lien N. Hoang, Narciso Olvera, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Anil K. Sood, Douglas A. Levine, Petar Jelinic
Published 2017-06-01

Pan-cancer genomic analysis links 3’UTR DNA methylation with increased gene expression in T cellsResearch in context

by Michael H. McGuire, Shelley M. Herbrich, Santosh K. Dasari, Sherry Y. Wu, Ying Wang, Rajesha Rupaimoole, Gabriel Lopez-Berestein, Keith A. Baggerly, Anil K. Sood
Published 2019-05-01

Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer.

by Ibrahim Tekedereli, S Neslihan Alpay, Clint D J Tavares, Zehra E Cobanoglu, Tamer S Kaoud, Ibrahim Sahin, Anil K Sood, Gabriel Lopez-Berestein, Kevin N Dalby, Bulent Ozpolat
Published 2012-01-01

PRKAR1B-AS2 Long Noncoding RNA Promotes Tumorigenesis, Survival, and Chemoresistance via the PI3K/AKT/mTOR Pathway

by Abdelrahman M. Elsayed, Emine Bayraktar, Paola Amero, Salama A. Salama, Abdelaziz H. Abdelaziz, Raed S. Ismail, Xinna Zhang, Cristina Ivan, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo
Published 2021-02-01

Presence of Circulating miR-145, miR-155, and miR-382 in Exosomes Isolated from Serum of Breast Cancer Patients and Healthy Donors

by Vianey Gonzalez-Villasana, Mohammed H. Rashed, Yessica Gonzalez-Cantú, Recep Bayraktar, Jorge Luis Menchaca-Arredondo, Jose Manuel Vazquez-Guillen, Cristina Rodriguez-Padilla, Gabriel Lopez-Berestein, Diana Resendez-Perez
Published 2019-01-01

Bone protection by inhibition of microRNA-182

by Kazuki Inoue, Zhonghao Deng, Yufan Chen, Eugenia Giannopoulou, Ren Xu, Shiaoching Gong, Matthew B. Greenblatt, Lingegowda S. Mangala, Gabriel Lopez-Berestein, David G. Kirsch, Anil K. Sood, Liang Zhao, Baohong Zhao
Published 2018-10-01

Neuropilin-2 mediated β-catenin signaling and survival in human gastro-intestinal cancer cell lines.

by Shaija Samuel, Puja Gaur, Fan Fan, Ling Xia, Michael J Gray, Nikolaos A Dallas, Debashish Bose, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Greg Plowman, Anil Bagri, Anil K Sood, Lee M Ellis
Published 2011-01-01

Inactivating Mutations of the <i>IK</i> Gene Weaken Ku80/Ku70-Mediated DNA Repair and Sensitize Endometrial Cancer to Chemotherapy

by Chao Gao, Guangxu Jin, Elizabeth Forbes, Lingegowda S. Mangala, Yingmei Wang, Cristian Rodriguez-Aguayo, Paola Amero, Emine Bayraktar, Ye Yan, Gabriel Lopez-Berestein, Russell R. Broaddus, Anil K. Sood, Fengxia Xue, Wei Zhang
Published 2021-05-01

ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer

by Aysegul Gorur, Recep Bayraktar, Cristina Ivan, Hamada Ahmed Mokhlis, Emine Bayraktar, Nermin Kahraman, Didem Karakas, Selda Karamil, Nashwa N. Kabil, Pinar Kanlikilicer, Burcu Aslan, Lulufer Tamer, Zhihui Wang, Vittorio Cristini, Gabriel Lopez-Berestein, George Calin, Bulent Ozpolat
Published 2021-03-01

Cystathionine beta-synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance.

by Sanjib Bhattacharyya, Sounik Saha, Karuna Giri, Ian R Lanza, K Sreekumar Nair, Nicholas B Jennings, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Eati Basal, Amy L Weaver, Daniel W Visscher, William Cliby, Anil K Sood, Resham Bhattacharya, Priyabrata Mukherjee
Published 2013-01-01

Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer

by Pradeep Chaluvally-Raghavan, Kang Jin Jeong, Sunila Pradeep, Andreia Machado Silva, Shuangxing Yu, Wenbin Liu, Tyler Moss, Cristian Rodriguez-Aguayo, Dong Zhang, Prahlad Ram, Jinsong Liu, Yiling Lu, Gabriel Lopez-Berestein, George A. Calin, Anil K. Sood, Gordon B. Mills
Published 2016-05-01

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axisResearch in context

by Cristian Rodriguez-Aguayo, Emine Bayraktar, Cristina Ivan, Burcu Aslan, Junhua Mai, Guangan He, Lingegowda S. Mangala, Dahai Jiang, Archana S. Nagaraja, Bulent Ozpolat, Arturo Chavez-Reyes, Mauro Ferrari, Rahul Mitra, Zahid H. Siddik, Haifa Shen, Xianbin Yang, Anil K. Sood, Gabriel Lopez-Berestein
Published 2019-02-01

CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis.

by Shu Zhang, Zhen Lu, Weiqun Mao, Ahmed A Ahmed, Hailing Yang, Jinhua Zhou, Nicholas Jennings, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Roberto Miranda, Wei Qiao, Veera Baladandayuthapani, Zongfang Li, Anil K Sood, Jinsong Liu, Xiao-Feng Le, Robert C Bast
Published 2015-01-01