A robust data-driven genomic signature for idiopathic pulmonary fibrosis with applications for translational model selection.

by Ron Ammar, Pitchumani Sivakumar, Gabor Jarai, John Ryan Thompson
Published 2019-01-01

Administration of bleomycin via the oropharyngeal aspiration route leads to sustained lung fibrosis in mice and rats as quantified by UTE-MRI and histology.

by Christine Egger, Catherine Cannet, Christelle Gérard, Elizabeth Jarman, Gabor Jarai, Agnès Feige, Thomas Suply, Arthur Micard, Andrew Dunbar, Bruno Tigani, Nicolau Beckmann
Published 2013-01-01

The anti-fibrotic effect of inhibition of TGFβ-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent γ-herpesvirus infection

by Natalia Smoktunowicz, Robert E. Alexander, Linda Franklin, Andrew E. Williams, Beverley Holman, Paul F. Mercer, Gabor Jarai, Chris J. Scotton, Rachel C. Chambers
Published 2015-09-01

SOMAscan Proteomics Identifies Serum Biomarkers Associated With Liver Fibrosis in Patients With NASH

by Yi Luo, Samir Wadhawan, Alex Greenfield, Benjamin E. Decato, Abdul M. Oseini, Rebecca Collen, Diane E. Shevell, John Thompson, Gabor Jarai, Edgar D. Charles, Arun J. Sanyal
Published 2021-05-01

RNA sequencing of transplant-stage idiopathic pulmonary fibrosis lung reveals unique pathway regulation

by Pitchumani Sivakumar, John Ryan Thompson, Ron Ammar, Mary Porteous, Carly McCoubrey, Edward Cantu, Kandasamy Ravi, Yan Zhang, Yi Luo, Denis Streltsov, Michael F. Beers, Gabor Jarai, Jason D. Christie
Published 2019-08-01

Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes.

by Nicolai A Kittan, Ronald M Allen, Abhay Dhaliwal, Karen A Cavassani, Matthew Schaller, Katherine A Gallagher, William F Carson, Sumanta Mukherjee, Jolanta Grembecka, Tomasz Cierpicki, Gabor Jarai, John Westwick, Steven L Kunkel, Cory M Hogaboam
Published 2013-01-01

Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases

by Mike Petrassi, Rob Barber, Celine Be, Sarah Beach, Brian Cox, Anne-Marie D’Souza, Nick Duggan, Martin Hussey, Roy Fox, Peter Hunt, Gabor Jarai, Takatoshi Kosaka, Paul Oakley, Viral Patel, Neil Press, David Rowlands, Clemens Scheufler, Oliver Schmidt, Honnappa Srinivas, Mary Turner, Rob Turner, John Westwick, Alison Wolfreys, Nuzhat Pathan, Simon Watson, Matthew Thomas, Matthew Thomas
Published 2017-05-01