Physical Computing and its Scope - Towards a Constructionist Computer Science Curriculum with Physical Computing

by Mareen PRZYBYLLA, Ralf ROMEIKE, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
Published 2014-10-01

Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[<i>e</i>]imidazo[2,1-<i>c</i>][1,2,4]triazines as Phosphodiesterase 2A Inhibitors

by Rien Ritawidya, Friedrich-Alexander Ludwig, Detlef Briel, Peter Brust, Matthias Scheunemann
Published 2019-07-01

LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[18F]Flubatine—A Positron Emission Tomography Radioligand for...

by Friedrich-Alexander Ludwig, René Smits, Steffen Fischer, Cornelius K. Donat, Alexander Hoepping, Peter Brust, Jörg Steinbach
Published 2016-09-01

Validation of an LC-MS/MS Method to Quantify the New TRPC6 Inhibitor SH045 (Larixyl <i>N</i>-methylcarbamate) and Its Application in an Exploratory Pharmacokinetic Study in Mice

by Xiao-Ning Chai, Friedrich-Alexander Ludwig, Anne Müglitz, Michael Schaefer, Hai-Yan Yin, Peter Brust, Ralf Regenthal, Ute Krügel
Published 2021-03-01

Exploring the Metabolism of (+)-[18F]Flubatine In Vitro and In Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study †

by Friedrich-Alexander Ludwig, Steffen Fischer, René Smits, Winnie Deuther-Conrad, Alexander Hoepping, Solveig Tiepolt, Marianne Patt, Osama Sabri, Peter Brust
Published 2018-02-01

Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain

by Katharina Holl, Dirk Schepmann, Steffen Fischer, Friedrich-Alexander Ludwig, Achim Hiller, Cornelius K. Donat, Winnie Deuther-Conrad, Peter Brust, Bernhard Wünsch
Published 2014-01-01

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tom...

by Rien Ritawidya, Barbara Wenzel, Rodrigo Teodoro, Magali Toussaint, Mathias Kranz, Winnie Deuther-Conrad, Sladjana Dukic-Stefanovic, Friedrich-Alexander Ludwig, Matthias Scheunemann, Peter Brust
Published 2019-11-01

Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant ¹⁸F-Labelled σ₂ Receptor Ligand

by Rareş-Petru Moldovan, Daniel Gündel, Rodrigo Teodoro, Friedrich-Alexander Ludwig, Steffen Fischer, Magali Toussaint, Dirk Schepmann, Bernhard Wünsch, Peter Brust, Winnie Deuther-Conrad
Published 2021-05-01

Sigma-1 Receptor Positron Emission Tomography: A New Molecular Imaging Approach Using (<i>S</i>)-(−)-[¹⁸F]Fluspidine in Glioblastoma

by Magali Toussaint, Winnie Deuther-Conrad, Mathias Kranz, Steffen Fischer, Friedrich-Alexander Ludwig, Tareq A. Juratli, Marianne Patt, Bernhard Wünsch, Gabriele Schackert, Osama Sabri, Peter Brust
Published 2020-05-01

Development of ¹⁸F-Labeled Radiotracers for PET Imaging of the Adenosine A_2A Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation

by Thu Hang Lai, Susann Schröder, Magali Toussaint, Sladjana Dukić-Stefanović, Mathias Kranz, Friedrich-Alexander Ludwig, Steffen Fischer, Jörg Steinbach, Winnie Deuther-Conrad, Peter Brust, Rareş-Petru Moldovan
Published 2021-02-01

Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain

by Jianrong Liu, Barbara Wenzel, Sladjana Dukic-Stefanovic, Rodrigo Teodoro, Friedrich-Alexander Ludwig, Winnie Deuther-Conrad, Susann Schröder, Jean-Michel Chezal, Emmanuel Moreau, Peter Brust, Aurélie Maisonial-Besset
Published 2016-04-01

Preclinical Evaluation of [¹⁸F]FACH in Healthy Mice and Piglets: An ¹⁸F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET

by Daniel Gündel, Masoud Sadeghzadeh, Winnie Deuther-Conrad, Barbara Wenzel, Paul Cumming, Magali Toussaint, Friedrich-Alexander Ludwig, Rareş-Petru Moldovan, Mathias Kranz, Rodrigo Teodoro, Bernhard Sattler, Osama Sabri, Peter Brust
Published 2021-02-01

Preclinical Incorporation Dosimetry of [¹⁸F]FACH—A Novel ¹⁸F-Labeled MCT1/MCT4 Lactate Transporter Inhibitor for Imaging Cancer Metabolism with PET

by Bernhard Sattler, Mathias Kranz, Barbara Wenzel, Nalin T. Jain, Rareş-Petru Moldovan, Magali Toussaint, Winnie Deuther-Conrad, Friedrich-Alexander Ludwig, Rodrigo Teodoro, Tatjana Sattler, Masoud Sadeghzadeh, Osama Sabri, Peter Brust
Published 2020-04-01

Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging

by Masoud Sadeghzadeh, Barbara Wenzel, Daniel Gündel, Winnie Deuther-Conrad, Magali Toussaint, Rareş-Petru Moldovan, Steffen Fischer, Friedrich-Alexander Ludwig, Rodrigo Teodoro, Shirisha Jonnalagadda, Sravan K. Jonnalagadda, Gerrit Schüürmann, Venkatram R. Mereddy, Lester R. Drewes, Peter Brust
Published 2020-05-01

In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine – A Radioligand for Imaging σ1 Receptors With Positron Emission Tomography (PET)

by Friedrich-Alexander Ludwig, Steffen Fischer, Richard Houska, Alexander Hoepping, Winnie Deuther-Conrad, Dirk Schepmann, Marianne Patt, Philipp M. Meyer, Swen Hesse, Swen Hesse, Georg-Alexander Becker, Franziska Ruth Zientek, Franziska Ruth Zientek, Jörg Steinbach, Bernhard Wünsch, Osama Sabri, Peter Brust
Published 2019-06-01

Konzept für ein VR-System zur intuitiven Modellierung durch natürliche Interaktion

by Fechter, Marius, Wartzack, Sandro
Published 2016

Wissensbasierter Aufbau konstruktions-begleitender Finite-Elemente-Analysen durch ein FEA-Assistenzsystem

by Kestel, Philipp, Wartzack, Sandro
Published 2016

EDEN

by Scholz, Martin
Published 2017

Considering emotional impressions in product design: Taking on the challenges ahead

by Kett, Susan Gretchen, Wartzack, Sandro
Published 2017

Das FEA-Assistenzsystem – Analyseteil FEdelM

by Spruegel, Tobias C., Wartzack, Sandro
Published 2016