A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy

by Frederick S. Varn, Yue Wang, Chao Cheng
Published 2019-01-01

Regulators associated with clinical outcomes revealed by DNA methylation data in breast cancer.

by Matthew H Ung, Frederick S Varn, Shaoke Lou, Chao Cheng
Published 2015-05-01

Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles

by Frederick S. Varn, Erik H. Andrews, David W. Mullins, Chao Cheng
Published 2016-01-01

Computational immune profiling in lung adenocarcinoma reveals reproducible prognostic associations with implications for immunotherapy

by Frederick S. Varn, Laura J. Tafe, Christopher I. Amos, Chao Cheng
Published 2018-06-01

The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients

by Kenneth M. K. Mark, Frederick S. Varn, Matthew H. Ung, Feng Qian, Chao Cheng
Published 2017-05-01

Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells

by Yanding Zhao, Robert Carter, Sivaraman Natarajan, Frederick S. Varn, Duane A. Compton, Charles Gawad, Chao Cheng, Kristina M. Godek
Published 2019-05-01

Perspective of mesenchymal transformation in glioblastoma

by Yona Kim, Frederick S. Varn, Sung-Hye Park, Byung Woo Yoon, Hye Ran Park, Charles Lee, Roel G. W. Verhaak, Sun Ha Paek
Published 2021-03-01

Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy

by Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, Hai Yan, Yiping He, Annick Desjardins, James E. Herndon, Frederick S. Varn, Roel G. Verhaak, Junfei Zhao, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, Frances McSherry, Andrea M. Muscat, Eric S. Lipp, Smita K. Nair, Mustafa Khasraw, Katherine B. Peters, Dina Randazzo, John H. Sampson, Roger E. McLendon, Darell D. Bigner, David M. Ashley
Published 2021-01-01