A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C.

by Robert Mintzer, Sreemathy Ramaswamy, Kinjalkumar Shah, Rami N Hannoush, Christine D Pozniak, Frederick Cohen, Xianrui Zhao, Emile Plise, Joseph W Lewcock, Christopher E Heise
Published 2012-01-01

Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6.

by Christopher E Heise, Jeremy Murray, Katherine E Augustyn, Brandon Bravo, Preeti Chugha, Frederick Cohen, Anthony M Giannetti, Paul Gibbons, Rami N Hannoush, Brian R Hearn, Priyadarshini Jaishankar, Cuong Q Ly, Kinjalkumar Shah, Karen Stanger, Micah Steffek, Yinyan Tang, Xianrui Zhao, Joseph W Lewcock, Adam R Renslo, John Flygare, Michelle R Arkin
Published 2012-01-01