Thymically-derived Foxp3+ regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model.

by Daniel R Holohan, Frédéric Van Gool, Jeffrey A Bluestone
Published 2019-01-01

Multiple Environmental Signaling Pathways Control the Differentiation of RORγt-Expressing Regulatory T Cells

by Hind Hussein, Sébastien Denanglaire, Frédéric Van Gool, Frédéric Van Gool, Abdulkader Azouz, Yousra Ajouaou, Hana El-Khatib, Guillaume Oldenhove, Oberdan Leo, Fabienne Andris
Published 2020-01-01

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD.

by Nathalie Busso, Mahir Karababa, Massimo Nobile, Aline Rolaz, Frédéric Van Gool, Mara Galli, Oberdan Leo, Alexander So, Thibaut De Smedt
Published 2008-01-01

ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.

by Benjamin Bondue, Olivier Vosters, Patricia de Nadai, Stéphanie Glineur, Olivier De Henau, Souphalone Luangsay, Frédéric Van Gool, David Communi, Paul De Vuyst, Daniel Desmecht, Marc Parmentier
Published 2011-11-01

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity

by David Wang, Jason Quiros, Kelly Mahuron, Chien-Chun Pai, Valeria Ranzani, Arabella Young, Stephanie Silveria, Tory Harwin, Arbi Abnousian, Massimiliano Pagani, Michael D. Rosenblum, Frederic Van Gool, Lawrence Fong, Jeffrey A. Bluestone, Michel DuPage
Published 2018-06-01

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28

by Yannick D. Muller, Yannick D. Muller, Yannick D. Muller, Duy P. Nguyen, Leonardo M. R. Ferreira, Leonardo M. R. Ferreira, Leonardo M. R. Ferreira, Patrick Ho, Patrick Ho, Patrick Ho, Caroline Raffin, Caroline Raffin, Roxxana Valeria Beltran Valencia, Zion Congrave-Wilson, Theodore L. Roth, Theodore L. Roth, Justin Eyquem, Frederic Van Gool, Frederic Van Gool, Alexander Marson, Alexander Marson, Alexander Marson, Laurent Perez, James A. Wells, James A. Wells, Jeffrey A. Bluestone, Jeffrey A. Bluestone, Qizhi Tang, Qizhi Tang
Published 2021-03-01