Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis.

by Laurens F M Verscheijden, Jan B Koenderink, Saskia N de Wildt, Frans G M Russel
Published 2019-06-01

Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis.

by Alwin Scharstuhl, Henricus A M Mutsaers, Sebastiaan W C Pennings, Frans G M Russel, Frank A D T G Wagener
Published 2009-01-01

Glutathione status and the renal elimination of inorganic mercury in the Mrp2(-/-) mouse.

by Christy C Bridges, Lucy Joshee, Jeroen J M W van den Heuvel, Frans G M Russel, Rudolfs K Zalups
Published 2013-01-01

Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children.

by Laurens F M Verscheijden, Carlijn H C Litjens, Jan B Koenderink, Ron H J Mathijssen, Marcel M Verbeek, Saskia N de Wildt, Frans G M Russel
Published 2021-03-01

Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

by Henricus A M Mutsaers, Lambertus P van den Heuvel, Lauke H J Ringens, Anita C A Dankers, Frans G M Russel, Jack F M Wetzels, Joost G Hoenderop, Rosalinde Masereeuw
Published 2011-04-01

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

by Maarten van der Velden, Albert Bilos, Jeroen J. M. W. van den Heuvel, Sanna R. Rijpma, Evelien G. E. Hurkmans, Robert W. Sauerwein, Frans G. M. Russel, Jan B. Koenderink
Published 2017-10-01

Aggregate dermal exposure to cyclic siloxanes in personal care products: Implications for risk assessment

by Jacqueline W.H. Biesterbos, Gwendolyn Beckmann, Luuk van Wel, Rob B.M. Anzion, Natalie von Goetz, Tatsiana Dudzina, Nel Roeleveld, Ad M.J. Ragas, Frans G.M. Russel, Paul T.J. Scheepers
Published 2015-01-01

Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule

by Nori J. L. Smeets, Carlijn H. C. Litjens, Jeroen J. M. W. van den Heuvel, Hedwig van Hove, Petra van den Broek, Frans G. M. Russel, Jan B. Koenderink, Saskia N. de Wildt
Published 2020-09-01

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

by Jan A J G van den Brand, Henricus A M Mutsaers, Arjan D van Zuilen, Peter J Blankestijn, Petra H van den Broek, Frans G M Russel, Rosalinde Masereeuw, Jack F M Wetzels
Published 2016-01-01

Identification of novel translational urinary biomarkers for acetaminophen-induced acute liver injury using proteomic profiling in mice.

by Rachel P L van Swelm, Coby M M Laarakkers, Ellen C van der Kuur, Eva Morava-Kozicz, Ron A Wevers, Kevin D Augustijn, Daan J Touw, Maro H Sandel, Rosalinde Masereeuw, Frans G M Russel
Published 2012-01-01

Deficiency of Either P-Glycoprotein or Breast Cancer Resistance Protein Protect against Acute Kidney Injury

by Miriam Huls, Joost P. H. Schoeber, Catherine M. Verfaillie, Aernout Luttun, Fernando Ulloa-Montoya, Aswin L. Menke, Lars R. Van Bolderen, Rob M. Woestenenk, Gerard F. M. Merkx, Jack F. M. Wetzels, Frans G. M. Russel, Rosalinde Masereeuw Ph.D.
Published 2010-09-01

Mass spectrometry analysis of hepcidin peptides in experimental mouse models.

by Harold Tjalsma, Coby M M Laarakkers, Rachel P L van Swelm, Milan Theurl, Igor Theurl, Erwin H Kemna, Yuri E M van der Burgt, Hanka Venselaar, Bas E Dutilh, Frans G M Russel, Günter Weiss, Rosalinde Masereeuw, Robert E Fleming, Dorine W Swinkels
Published 2011-01-01