Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive function.

by Lo-Kong Chan, Frankie Chi Fat Ko, Irene Oi-Lin Ng, Judy Wai Ping Yam
Published 2009-01-01

Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma.

by Jenny Chan, Frankie Chi Fat Ko, Yin-Shan Yeung, Irene Oi-Lin Ng, Judy Wai Ping Yam
Published 2011-02-01

Nuclear-targeted deleted in liver cancer 1 (DLC1) is less efficient in exerting its tumor suppressive activity both in vitro and in vivo.

by Lo-Kong Chan, Frankie Chi Fat Ko, Karen Man-Fong Sze, Irene Oi-Lin Ng, Judy Wai Ping Yam
Published 2011-01-01

Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery.

by Chun-Ming Wong, Carmen Chak-Lui Wong, Yeung-Lam Ng, Sandy Leung-Kuen Au, Frankie Chi-Fat Ko, Irene Oi-Lin Ng
Published 2011-01-01

Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma.

by Carmen Chak-Lui Wong, Chun-Ming Wong, Frankie Chi-Fat Ko, Lo-Kong Chan, Yick-Pang Ching, Judy Wai-Ping Yam, Irene Oi-lin Ng
Published 2008-07-01

Galectin-1 promotes hepatocellular carcinoma and the combined therapeutic effect of OTX008 galectin-1 inhibitor and sorafenib in tumor cells

by Zoe Leung, Frankie Chi Fat Ko, Sze Keong Tey, Ernest Man Lok Kwong, Xiaowen Mao, Bonnie Hei Man Liu, Angel Po Yee Ma, Yi Man Eva Fung, Chi-Ming Che, Danny Ka Ho Wong, Ching Lung Lai, Irene Oi-Lin Ng, Judy Wai Ping Yam
Published 2019-10-01