Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor

by Juergen Scharner, Sabrina Qi, Frank Rigo, C. Frank Bennett, Adrian R. Krainer
Published 2019-06-01

Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides

by Zhenxun Wang, Hyun Yong Jeon, Frank Rigo, C. Frank Bennett, Adrian R. Krainer
Published 2012-01-01

Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice

by Lodewijk J.A. Toonen, Frank Rigo, Haico van Attikum, Willeke M.C. van Roon-Mom
Published 2017-09-01

Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS

by Ghanashyam D. Ghadge, Yoshifumi Sonobe, Adrian Camarena, Claire Drigotas, Frank Rigo, Karen K. Ling, Raymond P. Roos
Published 2020-03-01

PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

by Allen T Yu, Carmen Berasain, Sonam Bhatia, Keith Rivera, Bodu Liu, Frank Rigo, Darryl J Pappin, David L Spector
Published 2021-05-01

Non-invasive monitoring of alternative splicing outcomes to identify candidate therapies for myotonic dystrophy type 1

by Ningyan Hu, Layal Antoury, Timothy M. Baran, Soumya Mitra, C. Frank Bennett, Frank Rigo, Thomas H. Foster, Thurman M. Wheeler
Published 2018-12-01

Antisense-mediated reduction of EphA4 in the adult CNS does not improve the function of mice with amyotrophic lateral sclerosis

by Karen K. Ling, Michaela Jackson, Duah Alkam, Dawei Liu, Norm Allaire, Chao Sun, Mahmoud Kiaei, Alexander McCampbell, Frank Rigo
Published 2018-06-01

Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration

by Sarah D. Diermeier, Kung-Chi Chang, Susan M. Freier, Junyan Song, Osama El Demerdash, Alexander Krasnitz, Frank Rigo, C. Frank Bennett, David L. Spector
Published 2016-09-01

Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells

by James J. Fink, Tiwanna M. Robinson, Noelle D. Germain, Carissa L. Sirois, Kaitlyn A. Bolduc, Amanda J. Ward, Frank Rigo, Stormy J. Chamberlain, Eric S. Levine
Published 2017-04-01

Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice

by Antonio Valencia, Veronica L. Reinhart Bieber, Bekim Bajrami, Galina Marsh, Stefan Hamann, Ru Wei, Karen Ling, Frank Rigo, H. Moore Arnold, Olga Golonzhka, Heike Hering
Published 2021-06-01

Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice

by Krista J. Spiller, Tahiyana Khan, Myrna A. Dominique, Clark R. Restrepo, Dejania Cotton-Samuel, Maya Levitan, Paymaan Jafar-Nejad, Bin Zhang, Armand Soriano, Frank Rigo, John Q. Trojanowski, Virginia M.-Y. Lee
Published 2019-04-01

MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

by Kung-Chi Chang, Sarah D. Diermeier, Allen T. Yu, Lily D. Brine, Suzanne Russo, Sonam Bhatia, Habeeb Alsudani, Karen Kostroff, Tawfiqul Bhuiya, Edi Brogi, Darryl J. Pappin, C. Frank Bennett, Frank Rigo, David L. Spector
Published 2020-12-01

Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.

by Hui-Min Cheng, Yijuang Chern, I-Hui Chen, Chia-Rung Liu, Sih-Huei Li, Seung J Chun, Frank Rigo, C Frank Bennett, Ning Deng, Yanan Feng, Chyuan-Sheng Lin, Yu-Ting Yan, Stanley N Cohen, Tzu-Hao Cheng
Published 2015-03-01

Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses

by Katannya Kapeli, Gabriel A. Pratt, Anthony Q. Vu, Kasey R. Hutt, Fernando J. Martinez, Balaji Sundararaman, Ranjan Batra, Peter Freese, Nicole J. Lambert, Stephanie C. Huelga, Seung J. Chun, Tiffany Y. Liang, Jeremy Chang, John P. Donohue, Lily Shiue, Jiayu Zhang, Haining Zhu, Franca Cambi, Edward Kasarskis, Shawn Hoon, Manuel Ares Jr., Christopher B. Burge, John Ravits, Frank Rigo, Gene W. Yeo
Published 2016-07-01

Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer

by Xiao Ling Li, Murugan Subramanian, Matthew F. Jones, Ritu Chaudhary, Deepak K. Singh, Xinying Zong, Berkley Gryder, Sivasish Sindri, Min Mo, Aaron Schetter, Xinyu Wen, Swetha Parvathaneni, Dickran Kazandjian, Lisa M. Jenkins, Wei Tang, Fathi Elloumi, Jennifer L. Martindale, Maite Huarte, Yuelin Zhu, Ana I. Robles, Susan M. Frier, Frank Rigo, Maggie Cam, Stefan Ambs, Sudha Sharma, Curtis C. Harris, Mary Dasso, Kannanganattu V. Prasanth, Ashish Lal
Published 2017-09-01