Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer.

by Silvia Pineda, Francisco X Real, Manolis Kogevinas, Alfredo Carrato, Stephen J Chanock, Núria Malats, Kristel Van Steen
Published 2015-12-01

BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis

by Laia Richart, Enrique Carrillo-de Santa Pau, Ana Río-Machín, Mónica P. de Andrés, Juan C. Cigudosa, Víctor J. Sánchez-Arévalo Lobo, Francisco X. Real
Published 2016-01-01

Correction: ARID1A Alterations Are Associated with FGFR3-Wild Type, Poor-Prognosis, Urothelial Bladder Tumors

by Cristina Balbás-Martínez, María Rodríguez-Pinilla, Ariel Casanova, Orlando Domínguez, David G. Pisano, Gonzalo Gómez, Josep Lloreta, José A. Lorente, Núria Malats, Francisco X. Real
Published 2014-01-01

ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors.

by Cristina Balbás-Martínez, María Rodríguez-Pinilla, Ariel Casanova, Orlando Domínguez, David G Pisano, Gonzalo Gómez, Josep Lloreta, José A Lorente, Núria Malats, Francisco X Real
Published 2013-01-01

Correction: ARID1A Alterations Are Associated with -Wild Type, Poor-Prognosis, Urothelial Bladder Tumors.

by Cristina Balbás-Martínez, María Rodríguez-Pinilla, Ariel Casanova, Orlando Domínguez, David G. Pisano, Gonzalo Gómez, Josep Lloreta, José A. Lorente, Núria Malats, Francisco X. Real
Published 2014-01-01

Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis

by Magali De Koninck, Eleonora Lapi, Claudio Badía-Careaga, Itziar Cossío, Daniel Giménez-Llorente, Miriam Rodríguez-Corsino, Elena Andrada, Andrés Hidalgo, Miguel Manzanares, Francisco X. Real, Ana Losada
Published 2020-08-01

Cyclooxygenase-2 expression in bladder cancer and patient prognosis: results from a large clinical cohort and meta-analysis.

by Maciej J Czachorowski, André F S Amaral, Santiago Montes-Moreno, Josep Lloreta, Alfredo Carrato, Adonina Tardón, Manuel M Morente, Manolis Kogevinas, Francisco X Real, Núria Malats, SBC/EPICURO investigators
Published 2012-01-01

Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity

by Catarina P. Santos, Eleonora Lapi, Jaime Martínez de Villarreal, Laura Álvaro-Espinosa, Asunción Fernández-Barral, Antonio Barbáchano, Orlando Domínguez, Ashley M. Laughney, Diego Megías, Alberto Muñoz, Francisco X. Real
Published 2019-09-01

Publisher Correction: Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice

by Marta Cáceres, Rita Quesada, Mar Iglesias, Francisco X. Real, Maria Villamonte, Jaime Martinez de Villarreal, Mónica Pérez, Ana Andaluz, Xavier Moll, Enrique Berjano, Dimitri Dorcaratto, Patricia Sánchez-Velázquez, Luís Grande, Fernando Burdío
Published 2021-03-01

Immunohistochemistry-Based Taxonomical Classification of Bladder Cancer Predicts Response to Neoadjuvant Chemotherapy

by Albert Font, Montserrat Domènech, Raquel Benítez, Marta Rava, Miriam Marqués, José L. Ramírez, Silvia Pineda, Sara Domínguez-Rodríguez, José L. Gago, Josep Badal, Cristina Carrato, Héctor López, Ariadna Quer, Daniel Castellano, Núria Malats, Francisco X. Real
Published 2020-07-01

Risk prediction scores for recurrence and progression of non-muscle invasive bladder cancer: an international validation in primary tumours.

by Moniek M Vedder, Mirari Márquez, Esther W de Bekker-Grob, Malu L Calle, Lars Dyrskjøt, Manoils Kogevinas, Ulrika Segersten, Per-Uno Malmström, Ferran Algaba, Willemien Beukers, Torben F Ørntoft, Ellen Zwarthoff, Francisco X Real, Nuria Malats, Ewout W Steyerberg
Published 2014-01-01

Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk.

by Montserrat García-Closas, Núria Malats, Francisco X Real, Meredith Yeager, Robert Welch, Debra Silverman, Manolis Kogevinas, Mustafa Dosemeci, Jonine Figueroa, Nilanjan Chatterjee, Adonina Tardón, Consol Serra, Alfredo Carrato, Reina García-Closas, Cristiane Murta-Nascimento, Nathaniel Rothman, Stephen J Chanock
Published 2007-02-01

GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1.

by Yi Zhong, Zheng Wang, Baojin Fu, Fan Pan, Shinichi Yachida, Mousumi Dhara, Emilia Albesiano, Li Li, Yoshiki Naito, Felip Vilardell, Christopher Cummings, Paola Martinelli, Ang Li, Raluca Yonescu, Qingyong Ma, Constance A Griffin, Francisco X Real, Christine A Iacobuzio-Donahue
Published 2011-01-01

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

by Petra van der Lelij, Simone Lieb, Julian Jude, Gordana Wutz, Catarina P Santos, Katrina Falkenberg, Andreas Schlattl, Jozef Ban, Raphaela Schwentner, Thomas Hoffmann, Heinrich Kovar, Francisco X Real, Todd Waldman, Mark A Pearson, Norbert Kraut, Jan-Michael Peters, Johannes Zuber, Mark Petronczki
Published 2017-07-01

Application of multi-SNP approaches Bayesian LASSO and AUC-RF to detect main effects of inflammatory-gene variants associated with bladder cancer risk.

by Evangelina López de Maturana, Yuanqing Ye, M Luz Calle, Nathaniel Rothman, Víctor Urrea, Manolis Kogevinas, Sandra Petrus, Stephen J Chanock, Adonina Tardón, Montserrat García-Closas, Anna González-Neira, Gemma Vellalta, Alfredo Carrato, Arcadi Navarro, Belén Lorente-Galdós, Debra T Silverman, Francisco X Real, Xifeng Wu, Núria Malats
Published 2013-01-01

Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.

by Silvia Pineda, Roger L Milne, M Luz Calle, Nathaniel Rothman, Evangelina López de Maturana, Jesús Herranz, Manolis Kogevinas, Stephen J Chanock, Adonina Tardón, Mirari Márquez, Lin T Guey, Montserrat García-Closas, Josep Lloreta, Erin Baum, Anna González-Neira, Alfredo Carrato, Arcadi Navarro, Debra T Silverman, Francisco X Real, Núria Malats
Published 2014-01-01

PIM kinases as potential therapeutic targets in a subset of peripheral T cell lymphoma cases.

by Esperanza Martín-Sánchez, Lina Odqvist, Socorro M Rodríguez-Pinilla, Margarita Sánchez-Beato, Giovanna Roncador, Beatriz Domínguez-González, Carmen Blanco-Aparicio, Ana M García Collazo, Esther González Cantalapiedra, Joaquín Pastor Fernández, Soraya Curiel del Olmo, Helena Pisonero, Rebeca Madureira, Carmen Almaraz, Manuela Mollejo, F Javier Alves, Javier Menárguez, Fernando González-Palacios, José Luis Rodríguez-Peralto, Pablo L Ortiz-Romero, Francisco X Real, Juan F García, James R Bischoff, Miguel A Piris
Published 2014-01-01

Large-scale pathway-based analysis of bladder cancer genome-wide association data from five studies of European background.

by Idan Menashe, Jonine D Figueroa, Montserrat Garcia-Closas, Nilanjan Chatterjee, Nuria Malats, Antoni Picornell, Dennis Maeder, Qi Yang, Ludmila Prokunina-Olsson, Zhaoming Wang, Francisco X Real, Kevin B Jacobs, Dalsu Baris, Michael Thun, Demetrius Albanes, Mark P Purdue, Manolis Kogevinas, Amy Hutchinson, Yi-Ping Fu, Wei Tang, Laurie Burdette, Adonina Tardón, Consol Serra, Alfredo Carrato, Reina García-Closas, Josep Lloreta, Alison Johnson, Molly Schwenn, Alan Schned, Gerald Andriole, Amanda Black, Eric J Jacobs, Ryan W Diver, Susan M Gapstur, Stephanie J Weinstein, Jarmo Virtamo, Neil E Caporaso, Maria Teresa Landi, Joseph F Fraumeni, Stephen J Chanock, Debra T Silverman, Nathaniel Rothman
Published 2012-01-01

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

by Sia Viborg Lindskrog, Frederik Prip, Philippe Lamy, Ann Taber, Clarice S. Groeneveld, Karin Birkenkamp-Demtröder, Jørgen Bjerggaard Jensen, Trine Strandgaard, Iver Nordentoft, Emil Christensen, Mateo Sokac, Nicolai J. Birkbak, Lasse Maretty, Gregers G. Hermann, Astrid C. Petersen, Veronika Weyerer, Marc-Oliver Grimm, Marcus Horstmann, Gottfrid Sjödahl, Mattias Höglund, Torben Steiniche, Karin Mogensen, Aurélien de Reyniès, Roman Nawroth, Brian Jordan, Xiaoqi Lin, Dejan Dragicevic, Douglas G. Ward, Anshita Goel, Carolyn D. Hurst, Jay D. Raman, Joshua I. Warrick, Ulrika Segersten, Danijel Sikic, Kim E. M. van Kessel, Tobias Maurer, Joshua J. Meeks, David J. DeGraff, Richard T. Bryan, Margaret A. Knowles, Tatjana Simic, Arndt Hartmann, Ellen C. Zwarthoff, Per-Uno Malmström, Núria Malats, Francisco X. Real, Lars Dyrskjøt
Published 2021-04-01

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

by Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso, Oscar Lao, Esther Molina-Montes, Isabel Adoración Martín-Antoniano, Paulina Gómez-Rubio, Rita Lawlor, Alfredo Carrato, Manuel Hidalgo, Mar Iglesias, Xavier Molero, Matthias Löhr, Christopher Michalski, José Perea, Michael O’Rorke, Victor Manuel Barberà, Adonina Tardón, Antoni Farré, Luís Muñoz-Bellvís, Tanja Crnogorac-Jurcevic, Enrique Domínguez-Muñoz, Thomas Gress, William Greenhalf, Linda Sharp, Luís Arnes, Lluís Cecchini, Joaquim Balsells, Eithne Costello, Lucas Ilzarbe, Jörg Kleeff, Bo Kong, Mirari Márquez, Josefina Mora, Damian O’Driscoll, Aldo Scarpa, Weimin Ye, Jingru Yu, PanGenEU Investigators, Montserrat García-Closas, Manolis Kogevinas, Nathaniel Rothman, Debra T Silverman, SBC/EPICURO Investigators, Demetrius Albanes, Alan A Arslan, Laura Beane-Freeman, Paige M Bracci, Paul Brennan, Bas Bueno-de-Mesquita, Julie Buring, Federico Canzian, Margaret Du, Steve Gallinger, J Michael Gaziano, Phyllis J Goodman, Marc Gunter, Loic LeMarchand, Donghui Li, Rachael E Neale, Ulrika Peters, Gloria M Petersen, Harvey A Risch, Maria José Sánchez, Xiao-Ou Shu, Mark D Thornquist, Kala Visvanathan, Wei Zheng, Stephen J Chanock, Douglas Easton, Brian M Wolpin, Rachael Z Stolzenberg-Solomon, Alison P Klein, Laufey T Amundadottir, Marc A Marti-Renom, Francisco X Real, Núria Malats
Published 2021-02-01