Deep sequencing of target linkage assay-identified regions in familial breast cancer: methods, analysis pipeline and troubleshooting.

by Juan Manuel Rosa-Rosa, Francisco Javier Gracia-Aznárez, Emily Hodges, Guillermo Pita, Michelle Rooks, Zhenyu Xuan, Arindam Bhattacharjee, Leonardo Brizuela, José M Silva, Gregory J Hannon, Javier Benitez
Published 2010-01-01

Machine Learning-Based Approach Highlights the Use of a Genomic Variant Profile for Precision Medicine in Ovarian Failure

by Ismael Henarejos-Castillo, Alejandro Aleman, Begoña Martinez-Montoro, Francisco Javier Gracia-Aznárez, Patricia Sebastian-Leon, Monica Romeu, Jose Remohi, Ana Patiño-Garcia, Pedro Royo, Gorka Alkorta-Aranburu, Patricia Diaz-Gimeno
Published 2021-06-01

Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles.

by Francisco Javier Gracia-Aznarez, Victoria Fernandez, Guillermo Pita, Paolo Peterlongo, Orlando Dominguez, Miguel de la Hoya, Mercedes Duran, Ana Osorio, Leticia Moreno, Anna Gonzalez-Neira, Juan Manuel Rosa-Rosa, Olga Sinilnikova, Sylvie Mazoyer, John Hopper, Conchi Lazaro, Melissa Southey, Fabrice Odefrey, Siranoush Manoukian, Irene Catucci, Trinidad Caldes, Henry T Lynch, Florentine S M Hilbers, Christi J van Asperen, Hans F A Vasen, David Goldgar, Paolo Radice, Peter Devilee, Javier Benitez
Published 2013-01-01