Tumor-Associated Glycans and Their Role in Gynecological Cancers: Accelerating Translational Research by Novel High-Throughput Approaches

by Tatiana Pochechueva, Francis Jacob, Andre Fedier, Viola Heinzelmann-Schwarz
Published 2012-11-01

Deciphering the Importance of Glycosphingolipids on Cellular and Molecular Mechanisms Associated with Epithelial-to-Mesenchymal Transition in Cancer

by Cécile Cumin, Yen-Lin Huang, Arun Everest-Dass, Francis Jacob
Published 2021-01-01

Novel Therapeutic Strategies for Ovarian Cancer Stem Cells

by Nastassja Terraneo, Francis Jacob, Anna Dubrovska, Anna Dubrovska, Anna Dubrovska, Anna Dubrovska, Jürgen Grünberg
Published 2020-03-01

Careful selection of reference genes is required for reliable performance of RT-qPCR in human normal and cancer cell lines.

by Francis Jacob, Rea Guertler, Stephanie Naim, Sheri Nixdorf, André Fedier, Neville F Hacker, Viola Heinzelmann-Schwarz
Published 2013-01-01

High‐grade serous peritoneal cancer follows a high stromal response signature and shows worse outcome than ovarian cancer

by Francis Jacob, Rosa Lina Marchetti, André B. Kind, Kenneth Russell, Andreas Schoetzau, Viola A. Heinzelmann‐Schwarz
Published 2021-01-01

Meta-Analysis of Microarray Data Identifies GAS6 Expression as an Independent Predictor of Poor Survival in Ovarian Cancer

by Michelle Buehler, Brian Tse, Alix Leboucq, Francis Jacob, Rosmarie Caduff, Daniel Fink, Darlene R. Goldstein, Viola Heinzelmann-Schwarz
Published 2013-01-01

ABO blood groups as a prognostic factor for recurrence in ovarian and vulvar cancer.

by Céline Montavon Sartorius, Andreas Schoetzau, Henriette Kettelhack, Daniel Fink, Neville F Hacker, André Fedier, Francis Jacob, Viola Heinzelmann-Schwarz
Published 2018-01-01

Blood Plasma-Derived Anti-Glycan Antibodies to Sialylated and Sulfated Glycans Identify Ovarian Cancer Patients.

by Tatiana Pochechueva, Alexander Chinarev, Andreas Schoetzau, André Fedier, Nicolai V Bovin, Neville F Hacker, Francis Jacob, Viola Heinzelmann-Schwarz
Published 2016-01-01

L1 Cell Adhesion Molecule Confers Radioresistance to Ovarian Cancer and Defines a New Cancer Stem Cell Population

by Nastassja Terraneo, Francis Jacob, Claudia Peitzsch, Anna Dubrovska, Christiane Krudewig, Yen-Lin Huang, Viola Heinzelmann-Schwarz, Roger Schibli, Martin Béhé, Jürgen Grünberg
Published 2020-01-01

Mucins and Truncated O-Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours

by Ricardo Coelho, Lara Marcos-Silva, Nuno Mendes, Daniela Pereira, Catarina Brito, Francis Jacob, Catharina Steentoft, Ulla Mandel, Henrik Clausen, Leonor David, Sara Ricardo
Published 2018-07-01

Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival

by Yen-Lin Huang, Ching-Yeu Liang, Vera Labitzky, Danilo Ritz, Tiago Oliveira, Cécile Cumin, Manuela Estermann, Tobias Lange, Arun V. Everest-Dass, Francis Jacob
Published 2021-10-01

Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion.

by Manuela Estermann, Yen-Lin Huang, Dedy Septiadi, Danilo Ritz, Ching-Yeu Liang, Francis Jacob, Barbara Drasler, Alke Petri-Fink, Viola Heinzelmann-Schwarz, Barbara Rothen-Rutishauser
Published 2020-01-01

Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients.

by Francis Jacob, Kristjan Ukegjini, Sheri Nixdorf, Caroline E Ford, Jake Olivier, Rosmarie Caduff, James P Scurry, Rea Guertler, Daniela Hornung, Renato Mueller, Daniel A Fink, Neville F Hacker, Viola A Heinzelmann-Schwarz
Published 2012-01-01

Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis

by Yen-Lin Huang, Ching-Yeu Liang, Danilo Ritz, Ricardo Coelho, Dedy Septiadi, Manuela Estermann, Cécile Cumin, Natalie Rimmer, Andreas Schötzau, Mónica Núñez López, André Fedier, Martina Konantz, Tatjana Vlajnic, Diego Calabrese, Claudia Lengerke, Leonor David, Barbara Rothen-Rutishauser, Francis Jacob, Viola Heinzelmann-Schwarz
Published 2020-10-01