The diverse mechanisms and anticancer potential of naphthoquinones

by Carolina Escardó Pereyra, Rafael Ferreira Dantas, Sabrina Baptista Ferreira, Luciano Pinho Gomes, Floriano Paes Silva-Jr
Published 2019-08-01

FindTargetsWEB: A User-Friendly Tool for Identification of Potential Therapeutic Targets in Metabolic Networks of Bacteria

by Thiago Castanheira Merigueti, Marcia Weber Carneiro, Ana Paula D’A. Carvalho-Assef, Floriano Paes Silva-Jr, Fabricio Alves Barbosa da Silva
Published 2019-07-01

Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling

by Ana Carolina Rennó Sodero, Bárbara Abrahim-Vieira, Pedro Henrique Monteiro Torres, Pedro Geraldo Pascutti, Célia RS Garcia, Vitor Francisco Ferreira, David Rodrigues da Rocha, Sabrina Baptista Ferreira, Floriano Paes Silva Jr

In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery

by Lauro Ribeiro de Souza Neto, José Teófilo Moreira-Filho, Bruno Junior Neves, Bruno Junior Neves, Rocío Lucía Beatriz Riveros Maidana, Rocío Lucía Beatriz Riveros Maidana, Ana Carolina Ramos Guimarães, Nicholas Furnham, Carolina Horta Andrade, Floriano Paes Silva
Published 2020-02-01

(Phenylamino)pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia

by Luiz Claudio Ferreira Pimentel, Lucas Villas Boas Hoelz, Henayle Fernandes Canzian, Frederico Silva Castelo Branco, Andressa Paula de Oliveira, Vinicius Rangel Campos, Floriano Paes Silva Júnior, Rafael Ferreira Dantas, Jackson Antônio Lamounier Camargos Resende, Anna Claudia Cunha, Nubia Boechat, Mônica Macedo Bastos
Published 2021-09-01

N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis

by Juciano Gasparotto, Alice Kunzler, Mario Roberto Senger, Celeste da Silva Freitas de Souza, Salvatore Giovanni de Simone, Rafael Calixto Bortolin, Nauana Somensi, Felipe Dal-Pizzol, José Claudio Fonseca Moreira, Ana Lúcia Abreu-Silva, Kátia da Silva Calabrese, Floriano Paes Silva Jr, Daniel Pens Gelain