Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells

by Emilia Vendelova, Diyaaeldin Ashour, Patrick Blank, Florian Erhard, Antoine-Emmanuel Saliba, Ulrich Kalinke, Manfred B. Lutz
Published 2018-02-01

Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9.

by Marie L Harth-Hertle, Barbara A Scholz, Florian Erhard, Laura V Glaser, Lars Dölken, Ralf Zimmer, Bettina Kempkes
Published 2013-09-01

Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation.

by Xiuye Wang, Liang Liu, Adam W Whisnant, Thomas Hennig, Lara Djakovic, Nabila Haque, Cindy Bach, Rozanne M Sandri-Goldin, Florian Erhard, Caroline C Friedel, Lars Dölken, Yongsheng Shi
Published 2021-03-01

Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27

by Xiuye Wang, Thomas Hennig, Adam W. Whisnant, Florian Erhard, Bhupesh K. Prusty, Caroline C. Friedel, Elmira Forouzmand, William Hu, Luke Erber, Yue Chen, Rozanne M. Sandri-Goldin, Lars Dölken, Yongsheng Shi
Published 2020-01-01

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes.

by Thomas Hennig, Marco Michalski, Andrzej J Rutkowski, Lara Djakovic, Adam W Whisnant, Marie-Sophie Friedl, Bhaskar Anand Jha, Marisa A P Baptista, Anne L'Hernault, Florian Erhard, Lars Dölken, Caroline C Friedel
Published 2018-03-01

EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.

by Laura V Glaser, Simone Rieger, Sybille Thumann, Sophie Beer, Cornelia Kuklik-Roos, Dietmar E Martin, Kerstin C Maier, Marie L Harth-Hertle, Björn Grüning, Rolf Backofen, Stefan Krebs, Helmut Blum, Ralf Zimmer, Florian Erhard, Bettina Kempkes
Published 2017-10-01

Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo.

by Lisa Marcinowski, Mélanie Tanguy, Astrid Krmpotic, Bernd Rädle, Vanda J Lisnić, Lee Tuddenham, Béatrice Chane-Woon-Ming, Zsolt Ruzsics, Florian Erhard, Corinna Benkartek, Marina Babic, Ralf Zimmer, Joanne Trgovcich, Ulrich H Koszinowski, Stipan Jonjic, Sébastien Pfeffer, Lars Dölken
Published 2012-02-01

ITN—VIROINF: Understanding (Harmful) Virus-Host Interactions by Linking Virology and Bioinformatics

by Winfried Goettsch, Niko Beerenwinkel, Li Deng, Lars Dölken, Bas E. Dutilh, Florian Erhard, Lars Kaderali, Max von Kleist, Roland Marquet, Jelle Matthijnssens, Shawna McCallin, Dino McMahon, Thomas Rattei, Ronald P. Van Rij, David L. Robertson, Martin Schwemmle, Noam Stern-Ginossar, Manja Marz
Published 2021-04-01

Integrative functional genomics decodes herpes simplex virus 1

by Adam W. Whisnant, Christopher S. Jürges, Thomas Hennig, Emanuel Wyler, Bhupesh Prusty, Andrzej J. Rutkowski, Anne L’hernault, Lara Djakovic, Margarete Göbel, Kristina Döring, Jennifer Menegatti, Robin Antrobus, Nicholas J. Matheson, Florian W. H. Künzig, Guido Mastrobuoni, Chris Bielow, Stefan Kempa, Chunguang Liang, Thomas Dandekar, Ralf Zimmer, Markus Landthaler, Friedrich Grässer, Paul J. Lehner, Caroline C. Friedel, Florian Erhard, Lars Dölken
Published 2020-04-01

HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy

by Jian Wang, Michael Weller, Roland Martin, Holger Moch, Julia Velz, Luca Regli, Hans-Georg Rammensee, Linus Backert, Oliver Kohlbacher, Ana Marcu, Leon Bichmann, Leon Kuchenbecker, Daniel Johannes Kowalewski, Lena Katharina Freudenmann, Lena Mühlenbruch, András Szolek, Maren Lübke, Philipp Wagner, Tobias Engler, Sabine Matovina, Mathias Hauri-Hohl, Konstantina Kapolou, Juliane Sarah Walz, Manuela Silginer, Markus W. Löffler, Florian Erhard, Andreas Schlosser, Stefan Stevanović, Marian Christoph Neidert
Published 2021-04-01