Type I PRMT Inhibition Protects Against C9ORF72 Arginine-Rich Dipeptide Repeat Toxicity

by Alan S. Premasiri, Anna L. Gill, Fernando G. Vieira
Published 2020-09-01

Hypothesis and Theory: Roles of Arginine Methylation in C9orf72-Mediated ALS and FTD

by Anna L. Gill, Alan S. Premasiri, Fernando G. Vieira
Published 2021-03-01

Dexpramipexole is ineffective in two models of ALS related neurodegeneration.

by Fernando G Vieira, Eva LaDow, Andy Moreno, Joshua D Kidd, Beth Levine, Kenneth Thompson, Alan Gill, Steven Finkbeiner, Steven Perrin
Published 2014-01-01

CuATSM efficacy is independently replicated in a SOD1 mouse model of ALS while unmetallated ATSM therapy fails to reveal benefits

by Fernando G. Vieira, Theo Hatzipetros, Kenneth Thompson, Andy J. Moreno, Joshua D. Kidd, Valerie R. Tassinari, Beth Levine, Steven Perrin, Alan Gill
Published 2017-06-01

Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.

by Fernando G Vieira, Qinggong Ping, Andy J Moreno, Joshua D Kidd, Kenneth Thompson, Bingbing Jiang, John M Lincecum, Monica Z Wang, Gerard S De Zutter, Valerie R Tassinari, Beth Levine, Theo Hatzipetros, Alan Gill, Steven Perrin
Published 2015-01-01