Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells

by Bettina Trinschek, Felix Luessi, Catharina C. Gross, Heinz Wiendl, Helmut Jonuleit
Published 2015-07-01

PPMS onset upon adalimumab treatment extends the spectrum of anti-TNF-α therapy-associated demyelinating disorders

by Sinah Engel, Felix Luessi, Aneka Mueller, Rudolf E. Schopf, Frauke Zipp, Stefan Bittner
Published 2020-01-01

Kinetics of IL-6 production defines T effector cell responsiveness to regulatory T cells in multiple sclerosis.

by Bettina Trinschek, Felix Luessi, Jürgen Haas, Brigitte Wildemann, Frauke Zipp, Heinz Wiendl, Christian Becker, Helmut Jonuleit
Published 2013-01-01

Implications of extreme serum neurofilament light chain levels for the management of patients with relapsing multiple sclerosis

by Sinah Engel, Maria Protopapa, Falk Steffen, Vakis Papanastasiou, Christoforos Nicolaou, Michalis Protopapas, Frauke Zipp, Stefan Bittner, Felix Luessi
Published 2021-04-01

Selective Brain Network and Cellular Responses Upon Dimethyl Fumarate Immunomodulation in Multiple Sclerosis

by Dumitru Ciolac, Dumitru Ciolac, Dumitru Ciolac, Felix Luessi, Gabriel Gonzalez-Escamilla, Nabin Koirala, Christian Riedel, Vinzenz Fleischer, Stefan Bittner, Julia Krämer, Sven G. Meuth, Muthuraman Muthuraman, Sergiu Groppa
Published 2019-07-01

Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase.

by Tina Leuenberger, Caspar F Pfueller, Felix Luessi, Ivo Bendix, Magdalena Paterka, Timour Prozorovski, Denise Treue, Sarah Luenstedt, Josephine Herz, Volker Siffrin, Carmen Infante-Duarte, Frauke Zipp, Sonia Waiczies
Published 2014-01-01

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.

by Janine Arloth, Gökcen Eraslan, Till F M Andlauer, Jade Martins, Stella Iurato, Brigitte Kühnel, Melanie Waldenberger, Josef Frank, Ralf Gold, Bernhard Hemmer, Felix Luessi, Sandra Nischwitz, Friedemann Paul, Heinz Wiendl, Christian Gieger, Stefanie Heilmann-Heimbach, Tim Kacprowski, Matthias Laudes, Thomas Meitinger, Annette Peters, Rajesh Rawal, Konstantin Strauch, Susanne Lucae, Bertram Müller-Myhsok, Marcella Rietschel, Fabian J Theis, Elisabeth B Binder, Nikola S Mueller
Published 2020-02-01

Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study

by Stefan Bittner, Falk Steffen, Timo Uphaus, Muthuraman Muthuraman, Vinzenz Fleischer, Anke Salmen, Felix Luessi, Achim Berthele, Luisa Klotz, Sven G. Meuth, Antonios Bayas, Friedemann Paul, Hans-Peter Hartung, Ralf Linker, Christoph Heesen, Martin Stangel, Brigitte Wildemann, Florian Then Bergh, Björn Tackenberg, Tania Kuempfel, Frank Weber, Uwe K. Zettl, Ulf Ziemann, Hayrettin Tumani, Sergiu Groppa, Mark Mühlau, Carsten Lukas, Bernhard Hemmer, Heinz Wiendl, Ralf Gold, Frauke Zipp
Published 2020-06-01

The Rare <i>IL22RA2</i> Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

by Paloma Gómez-Fernández, Aitzkoa Lopez de Lapuente Portilla, Ianire Astobiza, Jorge Mena, Andoni Urtasun, Vivian Altmann, Fuencisla Matesanz, David Otaegui, Elena Urcelay, Alfredo Antigüedad, Sunny Malhotra, Xavier Montalban, Tamara Castillo-Triviño, Laura Espino-Paisán, Orhan Aktas, Mathias Buttmann, Andrew Chan, Bertrand Fontaine, Pierre-Antoine Gourraud, Michael Hecker, Sabine Hoffjan, Christian Kubisch, Tania Kümpfel, Felix Luessi, Uwe K. Zettl, Frauke Zipp, Iraide Alloza, Manuel Comabella, Christina M. Lill, Koen Vandenbroeck
Published 2020-01-01