Retinal and Brain Organoids: Bridging the Gap Between in vivo Physiology and in vitro Micro-Physiology for the Study of Alzheimer’s Diseases

by Carlo Brighi, Carlo Brighi, Federica Cordella, Federica Cordella, Luigi Chiriatti, Alessandro Soloperto, Silvia Di Angelantonio, Silvia Di Angelantonio
Published 2020-06-01

Stem cell-based 3D brain organoids for mimicking, investigating, and challenging Alzheimer’s diseases

by Federica Cordella, Carlo Brighi, Alessandro Soloperto, Silvia Di Angelantonio
Published 2022-01-01

Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

by Carlo Brighi, Federico Salaris, Alessandro Soloperto, Federica Cordella, Silvia Ghirga, Valeria de Turris, Maria Rosito, Pier Francesca Porceddu, Chiara D’Antoni, Angelo Reggiani, Alessandro Rosa, Silvia Di Angelantonio
Published 2021-05-01

Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease

by Valentina Latina, Giacomo Giacovazzo, Federica Cordella, Bijorn Omar Balzamino, Alessandra Micera, Monica Varano, Cristina Marchetti, Francesca Malerba, Rita Florio, Bruno Bruni Ercole, Federico La Regina, Anna Atlante, Roberto Coccurello, Silvia Di Angelantonio, Pietro Calissano, Giuseppina Amadoro
Published 2021-03-01