Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma

by Mouadh Benamar, Fadila Guessous, Kangping Du, Patrick Corbett, Joseph Obeid, Daniel Gioeli, Craig L. Slingluff Jr, Tarek Abbas
Published 2016-08-01

A Novel PTEN/Mutant p53/c-Myc/Bcl-XL Axis Mediates Context-Dependent Oncogenic Effects of PTEN with Implications for Cancer Prognosis and Therapy

by Xiaoping Huang, Ying Zhang, Yaqiong Tang, Napoleon Butler, Jungeun Kim, Fadila Guessous, David Schiff, James Mandell, Roger Abounader
Published 2013-08-01