Local IFNα enhances the anti-tumoral efficacy of systemic anti-PD1 to prevent tumor relapse

by Maxime Thoreau, Fabienne Regnier, Alain Trautmann, Nadege Bercovici, Marion v Guerin, Lene Vimeux, Matthieu Benard, Hweixian L Penny
Published 2020-07-01

cAMP Bursts Control T Cell Directionality by Actomyosin Cytoskeleton Remodeling

by Morgane Simao, Fabienne Régnier, Sarah Taheraly, Achille Fraisse, Achille Fraisse, Rachida Tacine, Marie Fraudeau, Adam Benabid, Vincent Feuillet, Mireille Lambert, Jérôme Delon, Clotilde Randriamampita
Published 2021-05-01

The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression

by Julia M. Weiss, Marion V. Guérin, Fabienne Regnier, Gilles Renault, Isabelle Galy-Fauroux, Lene Vimeux, Vincent Feuillet, Elisa Peranzoni, Maxime Thoreau, Alain Trautmann, Nadège Bercovici
Published 2017-10-01

TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

by Marion V. Guerin, Fabienne Regnier, Vincent Feuillet, Lene Vimeux, Julia M. Weiss, Georges Bismuth, Gregoire Altan-Bonnet, Thomas Guilbert, Maxime Thoreau, Veronica Finisguerra, Emmanuel Donnadieu, Alain Trautmann, Nadège Bercovici
Published 2019-09-01

Early T cell signalling is reversibly altered in PD-1+ T lymphocytes infiltrating human tumors.

by Shu-Fang Wang, Stéphane Fouquet, Maxime Chapon, Hélène Salmon, Fabienne Regnier, Karine Labroquère, Cécile Badoual, Diane Damotte, Pierre Validire, Eve Maubec, Nicolas B Delongchamps, Aurélie Cazes, Laure Gibault, Marylène Garcette, Marie-Caroline Dieu-Nosjean, Marc Zerbib, Marie-Françoise Avril, Armelle Prévost-Blondel, Clotilde Randriamampita, Alain Trautmann, Nadège Bercovici
Published 2011-01-01