Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia

by F Esra Demircioglu, Brian A Sosa, Jessica Ingram, Hidde L Ploegh, Thomas U Schwartz
Published 2016-08-01

How lamina-associated polypeptide 1 (LAP1) activates Torsin

by Brian A Sosa, F Esra Demircioglu, James Z Chen, Jessica Ingram, Hidde L Ploegh, Thomas U Schwartz
Published 2014-08-01

The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn

by F. Esra Demircioglu, Weili Zheng, Alexander J. McQuown, Nolan K. Maier, Nicki Watson, Iain M. Cheeseman, Vladimir Denic, Edward H. Egelman, Thomas U. Schwartz
Published 2019-07-01