Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D pol

by Anna Dubankova, Jana Humpolickova, Martin Klima, Evzen Boura
Published 2017-12-01

Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

by Petra Krafcikova, Jan Silhan, Radim Nencka, Evzen Boura
Published 2020-07-01

Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes.

by Bartosz Różycki, Evzen Boura, James H Hurley, Gerhard Hummer
Published 2012-01-01

High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses

by Bara Cihlova, Andrea Huskova, Jiri Böserle, Radim Nencka, Evzen Boura, Jan Silhan
Published 2021-06-01

Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase

by Roberto Benoni, Petra Krafcikova, Marek R. Baranowski, Joanna Kowalska, Evzen Boura, Hana Cahová
Published 2021-08-01

Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein.

by Dhurvas Chandrasekaran Dinesh, Dominika Chalupska, Jan Silhan, Eliska Koutna, Radim Nencka, Vaclav Veverka, Evzen Boura
Published 2020-12-01

Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease

by Chandrabose Selvaraj, Umesh Panwar, Dhurvas Chandrasekaran Dinesh, Evzen Boura, Poonam Singh, Vikash Kumar Dubey, Sanjeev Kumar Singh
Published 2021-01-01

Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit

by Vladimira Horova, Barbora Landova, Jan Hodek, Karel Chalupsky, Petra Krafcikova, Dominika Chalupska, Vojtech Duchoslav, Jan Weber, Evzen Boura, Martin Klima
Published 2021-07-01

Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication

by Milan Dejmek, Eva Konkoľová, Luděk Eyer, Petra Straková, Pavel Svoboda, Michal Šála, Kateřina Krejčová, Daniel Růžek, Evzen Boura, Radim Nencka
Published 2021-08-01

Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites.

by Vladimira Horova, Heyrhyoung Lyoo, Bartosz Różycki, Dominika Chalupska, Miroslav Smola, Jana Humpolickova, Jeroen R P M Strating, Frank J M van Kuppeveld, Evzen Boura, Martin Klima
Published 2019-08-01

A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha[S]

by Nivedita Sengupta, Marko Jović, Elena Barnaeva, David W. Kim, Xin Hu, Noel Southall, Milan Dejmek, Ivana Mejdrova, Radim Nencka, Adriana Baumlova, Dominika Chalupska, Evzen Boura, Marc Ferrer, Juan Marugan, Tamas Balla
Published 2019-03-01

Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus

by Olivier Terrier, Sébastien Dilly, Andrés Pizzorno, Dominika Chalupska, Jana Humpolickova, Evžen Bouřa, Francis Berenbaum, Stéphane Quideau, Bruno Lina, Bruno Fève, Frédéric Adnet, Michèle Sabbah, Manuel Rosa-Calatrava, Vincent Maréchal, Julien Henri, Anny Slama-Schwok
Published 2021-04-01