A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties.

by Eun Suk Song, David W Rodgers, Louis B Hersh
Published 2010-03-01

Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation.

by Eun Suk Song, Manana Melikishvili, Michael G Fried, Maria A Juliano, Luiz Juliano, David W Rodgers, Louis B Hersh
Published 2012-01-01

Identification of the allosteric regulatory site of insulysin.

by Nicholas Noinaj, Sonia K Bhasin, Eun Suk Song, Kirsten E Scoggin, Maria A Juliano, Luiz Juliano, Louis B Hersh, David W Rodgers
Published 2011-01-01

An Extended Polyanion Activation Surface in Insulin Degrading Enzyme.

by Eun Suk Song, Mehmet Ozbil, Tingting Zhang, Michael Sheetz, David Lee, Danny Tran, Sheng Li, Rajeev Prabhakar, Louis B Hersh, David W Rodgers
Published 2015-01-01