Fibrosis, the Bad Actor in Cardiorenal Syndromes: Mechanisms Involved

by Beatriz Delgado-Valero, Victoria Cachofeiro, Ernesto Martínez-Martínez
Published 2021-07-01

Oxidative Stress and Vascular Damage in the Context of Obesity: The Hidden Guest

by Ernesto Martínez-Martínez, Francisco V. Souza-Neto, Sara Jiménez-González, Victoria Cachofeiro
Published 2021-03-01

A role for soluble ST2 in vascular remodeling associated with obesity in rats.

by Ernesto Martínez-Martínez, María Miana, Raquel Jurado-López, Elodie Rousseau, Patrick Rossignol, Faiez Zannad, Victoria Cachofeiro, Natalia López-Andrés
Published 2013-01-01

Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage.

by Ernesto Martinez-Martinez, Jaime Ibarrola, Laurent Calvier, Amaya Fernandez-Celis, Celine Leroy, Victoria Cachofeiro, Patrick Rossignol, Natalia Lopez-Andres
Published 2016-01-01

The endothelial αENaC contributes to vascular endothelial function in vivo.

by Antoine Tarjus, Martina Maase, Pia Jeggle, Ernesto Martinez-Martinez, Céline Fassot, Laurent Loufrani, Daniel Henrion, Pernille B L Hansen, Kristina Kusche-Vihrog, Frederic Jaisser
Published 2017-01-01

The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

by María Miana, María Galán, Ernesto Martínez-Martínez, Saray Varona, Raquel Jurado-López, Belén Bausa-Miranda, Alfonso Antequera, María Luaces, José Martínez-González, Cristina Rodríguez, Victoria Cachofeiro
Published 2015-06-01

The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats

by Sara Jiménez-González, Gema Marín-Royo, Raquel Jurado-López, María Visitación Bartolomé, Ana Romero-Miranda, María Luaces, Fabián Islas, María Luisa Nieto, Ernesto Martínez-Martínez, Victoria Cachofeiro
Published 2020-02-01

Beneficial Effects of Galectin-3 Blockade in Vascular and Aortic Valve Alterations in an Experimental Pressure Overload Model

by Jaime Ibarrola, Ernesto Martínez-Martínez, J. Rafael Sádaba, Vanessa Arrieta, Amaia García-Peña, Virginia Álvarez, Amaya Fernández-Celis, Alicia Gainza, Patrick Rossignol, Victoria Cachofeiro Ramos, Natalia López-Andrés
Published 2017-07-01

The Interplay of Mitochondrial Oxidative Stress and Endoplasmic Reticulum Stress in Cardiovascular Fibrosis in Obese Rats

by Francisco V. Souza-Neto, Sara Jiménez-González, Beatriz Delgado-Valero, Raquel Jurado-López, Marie Genty, Ana Romero-Miranda, Cristina Rodríguez, María Luisa Nieto, Ernesto Martínez-Martínez, Victoria Cachofeiro
Published 2021-08-01

Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity

by Gema Marín-Royo, Isabel Gallardo, Ernesto Martínez-Martínez, Beatriz Gutiérrez, Raquel Jurado-López, Natalia López-Andrés, Josué Gutiérrez-Tenorio, Eduardo Rial, Marı́a Visitación Bartolomé, María Luisa Nieto, Victoria Cachofeiro
Published 2018-02-01

Antifibrotic effect of novel neutrophil gelatinase-associated lipocalin inhibitors in cardiac and renal disease models

by Benjamin Bonnard, Ernesto Martínez-Martínez, Amaya Fernández-Celis, Marie Pieronne-Deperrois, Quoc-Tuan Do, Isbaal Ramos, Patrick Rossignol, Faiez Zannad, Paul Mulder, Antoine Ouvrard-Pascaud, Natalia López-Andrés, Frédéric Jaisser
Published 2021-01-01

The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats

by Adriana Ortega-Hernández, Ernesto Martínez-Martínez, Ruben Gómez-Gordo, Natalia López-Andrés, Amaya Fernández-Celis, Beatriz Gutiérrrez-Miranda, María Luisa Nieto, Teresa Alarcón, Claudio Alba, Dulcenombre Gómez-Garre, Victoria Cachofeiro
Published 2020-07-01

DIOL triterpenes block profibrotic effects of angiotensin II and protect from cardiac hypertrophy.

by Ruben Martín, Maria Miana, Raquel Jurado-López, Ernesto Martínez-Martínez, Nieves Gómez-Hurtado, Carmen Delgado, Maria Visitación Bartolomé, José Alberto San Román, Claudia Cordova, Vicente Lahera, Maria Luisa Nieto, Victoria Cachofeiro
Published 2012-01-01

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12

by Jaime Ibarrola, Rafael Sadaba, Ernesto Martinez-Martinez, Amaia Garcia-Peña, Vanessa Arrieta, Virginia Alvarez, Amaya Fernández-Celis, Alicia Gainza, Victoria Cachofeiro, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Frederic Jaisser, Natalia Lopez-Andres
Published 2018-05-01

Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1

by Lara Matilla, Vanessa Arrieta, Eva Jover, Amaia Garcia-Peña, Ernesto Martinez-Martinez, Rafael Sadaba, Virginia Alvarez, Adela Navarro, Amaya Fernandez-Celis, Alicia Gainza, Enrique Santamaria, Joaquín Fernandez-Irigoyen, Patrick Rossignol, Faiez Zannad, Natalia Lopez-Andres
Published 2020-07-01