A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

by Felix Poppelaars, Elena Goicoechea de Jorge, Ilse Jongerius, Ilse Jongerius, Antje J. Baeumner, Mark-Steven Steiner, Mihály Józsi, Mihály Józsi, Erik J. M. Toonen, Diana Pauly, Diana Pauly, the SciFiMed consortium
Published 2021-03-01

Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance

by Erik J M Toonen, Andreea-Manuela Mirea, Cees J Tack, Rinke Stienstra, Dov B Ballak, Janna A van Diepen, Anneke Hijmans, Triantafyllos Chavakis, Wim H Dokter, Christine T N Pham, Mihai G Netea, Charles A Dinarello, Leo A B Joosten
Published 2016-05-01

Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis.

by Erik J M Toonen, Christian Gilissen, Barbara Franke, Wietske Kievit, Agnes M Eijsbouts, Alfons A den Broeder, Simon V van Reijmersdal, Joris A Veltman, Hans Scheffer, Timothy R D J Radstake, Piet L C M van Riel, Pilar Barrera, Marieke J H Coenen
Published 2012-01-01

Complement-mediated Damage to the Glycocalyx Plays a Role in Renal Ischemia-reperfusion Injury in Mice

by Anjan K. Bongoni, PhD, Bo Lu, PhD, Jennifer L. McRae, PhD, Evelyn J. Salvaris, BSc (Hons), Erik J. M. Toonen, PhD, Ingela Vikstrom, PhD, Adriana Baz Morelli, PhD, Martin J. Pearse, PhD, Peter J. Cowan, PhD
Published 2019-04-01

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

by Andreea-Manuela Mirea, Erik J. M. Toonen, Inge van den Munckhof, Isabelle D. Munsterman, Eric T. T. L. Tjwa, Martin Jaeger, Marije Oosting, Kiki Schraa, Joost H. W. Rutten, Marinette van der Graaf, Niels P. Riksen, Jacqueline de Graaf, Mihai G. Netea, Cees J. Tack, Triantafyllos Chavakis, Leo A. B. Joosten
Published 2019-05-01

Glucose kinetics in the collagen-induced arthritis model: an all-in-one model to assess both efficacy and metabolic side effects of glucocorticoids.

by Erik J M Toonen, Anke J Laskewitz, Theo H van Dijk, Aycha Bleeker, Aldo Grefhorst, Annelies E Schouten, Ellen A J Bastiaanssen, Dov B Ballak, Marije I Koenders, Cindy van Doorn, Monique A J van der Vleuten, Marie-Jose C van Lierop, Albert K Groen, Wim H A Dokter
Published 2014-01-01

Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.

by Marieke J H Coenen, Christian Enevold, Pilar Barrera, Mascha M V A P Schijvenaars, Erik J M Toonen, Hans Scheffer, Leonid Padyukov, Alf Kastbom, Lars Klareskog, Anne Barton, Wietske Kievit, Maarten J Rood, Tim L Jansen, Dorine Swinkels, Piet L C M van Riel, Barbara Franke, Klaus Bendtzen, Timothy R D J Radstake
Published 2010-12-01

Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

by Matthew S. Buckland, James B. Galloway, Caoimhe Nic Fhogartaigh, Luke Meredith, Nicholas M. Provine, Stuart Bloor, Ane Ogbe, Wioleta M. Zelek, Anna Smielewska, Anna Yakovleva, Tiffeney Mann, Laura Bergamaschi, Lorinda Turner, Frederica Mescia, Erik J. M. Toonen, Carl-Philipp Hackstein, Hossain Delowar Akther, Vinicius Adriano Vieira, Lourdes Ceron-Gutierrez, Jimstan Periselneris, Sorena Kiani-Alikhan, Sofia Grigoriadou, Devan Vaghela, Sara E. Lear, M. Estée Török, William L. Hamilton, Joanne Stockton, Josh Quick, Peter Nelson, Michael Hunter, Tanya I. Coulter, Lisa Devlin, CITIID-NIHR COVID-19 BioResource Collaboration, MRC-Toxicology Unit COVID-19 Consortium, John R. Bradley, Kenneth G. C. Smith, Willem H. Ouwehand, Lise Estcourt, Heli Harvala, David J. Roberts, Ian B. Wilkinson, Nick Screaton, Nicholas Loman, Rainer Doffinger, Paul A. Lyons, B. Paul Morgan, Ian G. Goodfellow, Paul Klenerman, Paul J. Lehner, Nicholas J. Matheson, James E. D. Thaventhiran
Published 2020-12-01