Dissecting the Link Between Calcification and Macrophage led Inflammation in Atherosclerosis

by Olivia J. Waring, Han Jin, Jan Nagenborg, Pieter Goossens, Marjo M.P.C. Donners, Erik A.L. Biessen
Published 2020-01-01

MicroRNAs in Chronic Kidney Disease: Four Candidates for Clinical Application

by Linsey J. F. Peters, Jürgen Floege, Erik A. L. Biessen, Joachim Jankowski, Emiel P. C. van der Vorst
Published 2020-09-01

Whole-Body Prolyl Hydroxylase Domain (PHD) 3 Deficiency Increased Plasma Lipids and Hematocrit Without Impacting Plaque Size in Low-Density Lipoprotein Receptor Knockout Mice

by Jasper A. F. Demandt, Kim van Kuijk, Kim van Kuijk, Thomas L. Theelen, Elke Marsch, Sean P. Heffron, Edward A. Fisher, Peter Carmeliet, Peter Carmeliet, Erik A. L. Biessen, Erik A. L. Biessen, Judith C. Sluimer, Judith C. Sluimer
Published 2021-05-01

A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

by Renée J. H. A. Tillie, Thomas L. Theelen, Kim van Kuijk, Lieve Temmerman, Jenny de Bruijn, Marion Gijbels, Christer Betsholtz, Erik A. L. Biessen, Judith C. Sluimer
Published 2021-07-01

Peptide Antagonists for P-selectin Discriminate between Sulfatide-Dependent Platelet Aggregation and PSGL-1-Mediated Cell Adhesion

by Suzanne J.A. Korporaal, Tom J.M. Molenaar, Bianca C.H. Lutters, Illiana Meurs, Sandra Drost-Verhoef, Johan Kuiper, Theo J.C. van Berkel, Erik A.L. Biessen
Published 2019-08-01

Small Things Matter: Relevance of MicroRNAs in Cardiovascular Disease

by Linsey J. F. Peters, Linsey J. F. Peters, Linsey J. F. Peters, Linsey J. F. Peters, Erik A. L. Biessen, Erik A. L. Biessen, Mathias Hohl, Christian Weber, Christian Weber, Christian Weber, Christian Weber, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Emiel P. C. van der Vorst, Donato Santovito, Donato Santovito
Published 2020-07-01

Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.

by Carlos L J Vrins, Ruud Out, Peter van Santbrink, André van der Zee, Tokameh Mahmoudi, Martine Groenendijk, Louis M Havekes, Theo J C van Berkel, Ko Willems van Dijk, Erik A L Biessen
Published 2013-01-01

Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation[S]

by Martine Bot, Saskia C.A. de Jager, Luke MacAleese, H. Maxime Lagraauw, Theo J.C. van Berkel, Paul H.A. Quax, Johan Kuiper, Ron M.A. Heeren, Erik A.L. Biessen, Ilze Bot
Published 2013-05-01

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet.

by Dennis H M Kusters, Martijn L Chatrou, Brecht A G Willems, Marijke De Saint-Hubert, Matthias Bauwens, Emiel van der Vorst, Stefania Bena, Erik A L Biessen, Mauro Perretti, Leon J Schurgers, Chris P M Reutelingsperger
Published 2015-01-01

Development of the BioHybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells and Blood to Measure Vascular Calcification Propensity

by Armand M. G. Jaminon, Asim C. Akbulut, Niko Rapp, Rafael Kramann, Erik A. L. Biessen, Lieve Temmerman, Barend Mees, Vincent Brandenburg, Robert Dzhanaev, Willi Jahnen-Dechent, Juergen Floege, Jouni Uitto, Chris P. Reutelingsperger, Leon J. Schurgers
Published 2021-08-01

Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe −/− mice

by Sai Sahana Sundararaman, Linsey J. F. Peters, Yvonne Jansen, Selin Gencer, Yi Yan, Sumra Nazir, Andrea Bonnin Marquez, Florian Kahles, Michael Lehrke, Erik A. L. Biessen, Joachim Jankowski, Christian Weber, Yvonne Döring, Emiel P. C. van der Vorst
Published 2021-05-01

Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes.

by Saskia C A de Jager, Brenda W C Bongaerts, Michael Weber, Adriaan O Kraaijeveld, Mat Rousch, Stefanie Dimmeler, Marja P van Dieijen-Visser, Kitty B J M Cleutjens, Patty J Nelemans, Theo J C van Berkel, Erik A L Biessen
Published 2012-01-01

Leukocyte Bim deficiency does not impact atherogenesis in ldlr −/− mice, despite a pronounced induction of autoimmune inflammation

by Lieve Temmerman, Marijke M. Westra, Ilze Bot, Bart J. M. van Vlijmen, Niek van Bree, Martine Bot, Kim L. L. Habets, Tom G. H. Keulers, Johan van der Vlag, Thomas G. Cotter, Theo J. C. van Berkel, Erik A. L. Biessen
Published 2017-06-01

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice.

by Marjo M P C Donners, Lili Bai, Suzanne P M Lutgens, Erwin Wijnands, Jason Johnson, Leon J Schurgers, Cong-Lin Liu, Mat J A P Daemen, Kitty B J M Cleutjens, Guo-Ping Shi, Erik A L Biessen, Sylvia Heeneman
Published 2016-01-01

Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro.

by Kasinath Viswanathan, Ilze Bot, Liying Liu, Erbin Dai, Peter C Turner, Babajide Togonu-Bickersteth, Jakob Richardson, Jennifer A Davids, Jennifer M Williams, Mee Y Bartee, Hao Chen, Theo J C van Berkel, Erik A L Biessen, Richard W Moyer, Alexandra R Lucas
Published 2012-01-01

Prediction Power on Cardiovascular Disease of Neuroimmune Guidance Cues Expression by Peripheral Blood Monocytes Determined by Machine-Learning Methods

by Huayu Zhang, Edwin O. W. Bredewold, Dianne Vreeken, Jacques. M. G. J. Duijs, Hetty C. de Boer, Adriaan O. Kraaijeveld, J. Wouter Jukema, Nico H. Pijls, Johannes Waltenberger, Erik A.L. Biessen, Eric P. van der Veer, Anton Jan van Zonneveld, Janine M. van Gils
Published 2020-09-01

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

by Johanna P. van Geffen, Frauke Swieringa, Kim van Kuijk, Bibian M. E. Tullemans, Fiorella A. Solari, Bing Peng, Kenneth J. Clemetson, Richard W. Farndale, Ludwig J. Dubois, Albert Sickmann, René P. Zahedi, Robert Ahrends, Erik A. L. Biessen, Judith C. Sluimer, Johan W. M. Heemskerk, Marijke J. E. Kuijpers
Published 2020-12-01

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

by Till Seime, Asim Cengiz Akbulut, Moritz Lindquist Liljeqvist, Antti Siika, Hong Jin, Greg Winski, Rick H. van Gorp, Eva Karlöf, Mariette Lengquist, Andrew J. Buckler, Malin Kronqvist, Olivia J. Waring, Jan H. N. Lindeman, Erik A. L. Biessen, Lars Maegdefessel, Anton Razuvaev, Leon J. Schurgers, Ulf Hedin, Ljubica Matic
Published 2021-05-01

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dep...

by Julian I Borissoff, Jeroen J T Otten, Sylvia Heeneman, Peter Leenders, René van Oerle, Oliver Soehnlein, Sarah T B G Loubele, Karly Hamulyák, Tilman M Hackeng, Mat J A P Daemen, Jay L Degen, Hartmut Weiler, Charles T Esmon, Joanne van Ryn, Erik A L Biessen, Henri M H Spronk, Hugo ten Cate
Published 2013-01-01

Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice.

by Martine Bot, Paul P Van Veldhoven, Saskia C A de Jager, Jason Johnson, Niels Nijstad, Peter J Van Santbrink, Marijke M Westra, Gerd Van Der Hoeven, Marion J Gijbels, Carsten Müller-Tidow, Georg Varga, Uwe J F Tietge, Johan Kuiper, Theo J C Van Berkel, Jerzy-Roch Nofer, Ilze Bot, Erik A L Biessen
Published 2013-01-01