ATF6 as a Nodal Regulator of Proteostasis in the Heart

by Christopher C. Glembotski, Adrian Arrieta, Erik A. Blackwood, Winston T. Stauffer
Published 2020-04-01

Integrating ER and Mitochondrial Proteostasis in the Healthy and Diseased Heart

by Adrian Arrieta, Erik A. Blackwood, Winston T. Stauffer, Christopher C. Glembotski
Published 2020-01-01

Sledgehammer to Scalpel: Broad Challenges to the Heart and Other Tissues Yield Specific Cellular Responses via Transcriptional Regulation of the ER-Stress Master Regulator ATF6α

by Winston T. Stauffer, Adrian Arrieta, Erik A. Blackwood, Christopher C. Glembotski
Published 2020-02-01

Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis

by Erik A. Blackwood, Alina S. Bilal, Winston T. Stauffer, Adrian Arrieta, Christopher C. Glembotski
Published 2020-03-01

The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts

by Winston T. Stauffer, Erik A. Blackwood, Khalid Azizi, Randal J. Kaufman, Christopher C. Glembotski
Published 2020-02-01

Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins

by Ryan Paxman, Lars Plate, Erik A Blackwood, Chris Glembotski, Evan T Powers, R Luke Wiseman, Jeffery W Kelly
Published 2018-08-01

Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis

by Erik A. Blackwood, Khalid Azizi, Donna J. Thuerauf, Ryan J. Paxman, Lars Plate, Jeffery W. Kelly, R. Luke Wiseman, Christopher C. Glembotski
Published 2019-01-01