σ₂ Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach

by Francesca Serena Abatematteo, Mauro Niso, Enza Lacivita, Carmen Abate
Published 2021-06-01

Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2

by Sabina Podlewska, Ryszard Bugno, Enza Lacivita, Marcello Leopoldo, Andrzej J. Bojarski, Jadwiga Handzlik
Published 2021-01-01

Synthesis and biological evaluation of potential positron emission tomography (PET) ligands for brain visualization of dopamine D3 receptors

by Enza Lacivita, Francesco Berardi, Nicola A. Colabufo, Marcello Leopoldo, Roberto Perrone, Vincenzo Tortorella
Published 2006-08-01

The brain-penetrant 5-HT7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain

by Mirko Santello, Alberto Bisco, Natalie Elisabeth Nevian, Enza Lacivita, Marcello Leopoldo, Thomas Nevian
Published 2017-10-01

Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice

by Kadriye DEMİRKAYA, Özlem Martı AKGÜN, Buğra ŞENEL, Zeynep ÖNCEL TORUN, Melik SEYREK, Enza LACİVİTA, Marcello LEOPOLDO, Ahmet DOĞRUL

The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Exhibits Anti-Inflammatory Activity in LPS-Stimulated Organotypic Hippocampal Cultures

by Ewa Trojan, Kinga Tylek, Monika Leśkiewicz, Władysław Lasoń, Lars-Ove Brandenburg, Marcello Leopoldo, Enza Lacivita, Agnieszka Basta-Kaim
Published 2021-06-01

Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways

by Kinga Tylek, Ewa Trojan, Monika Leśkiewicz, Magdalena Regulska, Natalia Bryniarska, Katarzyna Curzytek, Enza Lacivita, Marcello Leopoldo, Agnieszka Basta-Kaim
Published 2021-09-01

Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT₇ Receptor

by Alessandra Tempio, Mauro Niso, Luna Laera, Lucia Trisolini, Maria Favia, Lucia Ciranna, Domenico Marzulli, Giuseppe Petrosillo, Ciro Leonardo Pierri, Enza Lacivita, Marcello Leopoldo
Published 2020-12-01

Prior Activation of 5-HT7 Receptors Modulates the Conditioned Place Preference With Methylphenidate

by Cristiana Carbone, Sara Lucia Maria Lo Russo, Enza Lacivita, Annika Frank, Enrico Alleva, Holger Stark, Luciano Saso, Marcello Leopoldo, Marcello Leopoldo, Walter Adriani
Published 2019-09-01

Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile...

by Lara Costa, Lara Maria Sardone, Carmela Maria Bonaccorso, Simona D’Antoni, Michela Spatuzza, Walter Gulisano, Maria Rosaria Tropea, Daniela Puzzo, Marcello Leopoldo, Enza Lacivita, Maria Vincenza Catania, Maria Vincenza Catania, Lucia Ciranna
Published 2018-10-01

Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fr...

by Lucia A Ruocco, Concetta Treno, Ugo A Gironi Carnevale, Claudio Arra, Gianpiero Boatto, Maria Nieddu, Cristina Pagano, Placido Illiano, Fabiana Barbato, Angela Tino, Ezio Carboni, Giovanni Laviola, Enza Lacivita, Marcello Leopoldo, Walter Adriani, Adolfo G Sadile
Published 2014-01-01