Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS.

by Lucas E Cavallin, Pascal Goldschmidt-Clermont, Enrique A Mesri
Published 2014-07-01

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication.

by Brittany M Ashlock, Qi Ma, Biju Issac, Enrique A Mesri
Published 2014-01-01

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded Viral IL-6 (vIL-6) Enhances Immunoglobulin Class-Switch Recombination

by Santas A. Rosario, Santas A. Rosario, Santas A. Rosario, Gabriel E. Santiago, Gabriel E. Santiago, Gabriel E. Santiago, Enrique A. Mesri, Enrique A. Mesri, Enrique A. Mesri, Ramiro E. Verdun, Ramiro E. Verdun, Ramiro E. Verdun
Published 2018-12-01

A role of hypoxia-inducible factor 1 alpha in Murine Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency.

by Darlah M López-Rodríguez, Varvara Kirillov, Laurie T Krug, Enrique A Mesri, Samita Andreansky
Published 2019-12-01

High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.

by Julian Naipauer, Daria Salyakina, Guy Journo, Santas Rosario, Sion Williams, Martin Abba, Meir Shamay, Enrique A Mesri
Published 2020-06-01

A Non-Coding RNA Network Involved in KSHV Tumorigenesis

by Julián Naipauer, Julián Naipauer, Martín E. García Solá, Martín E. García Solá, Martín E. García Solá, Daria Salyakina, Santas Rosario, Sion Williams, Sion Williams, Omar Coso, Omar Coso, Omar Coso, Martín C. Abba, Martín C. Abba, Enrique A. Mesri, Enrique A. Mesri, Ezequiel Lacunza, Ezequiel Lacunza
Published 2021-06-01

KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis.

by Lucas E Cavallin, Qi Ma, Julian Naipauer, Sachin Gupta, Mani Kurian, Paola Locatelli, Paolo Romanelli, Mehrdad Nadji, Pascal J Goldschmidt-Clermont, Enrique A Mesri
Published 2018-07-01

KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi's sarcoma.

by María Victoria Medina, Agata D Agostino, Qi Ma, Pilar Eroles, Lucas Cavallin, Chiara Chiozzini, Daiana Sapochnik, Cora Cymeryng, Elizabeth Hyjek, Ethel Cesarman, Julian Naipauer, Enrique A Mesri, Omar A Coso
Published 2020-10-01

PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.

by Julian Naipauer, Santas Rosario, Sachin Gupta, Courtney Premer, Omayra Méndez-Solís, Mariana Schlesinger, Virginia Ponzinibbio, Vaibhav Jain, Lauren Gay, Rolf Renne, Ho Lam Chan, Lluis Morey, Daria Salyakina, Martin Abba, Sion Williams, Joshua M Hare, Pascal J Goldschmidt-Clermont, Enrique A Mesri
Published 2019-12-01