Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific.

by Claire Hippert, Anna B Graca, Amanda C Barber, Emma L West, Alexander J Smith, Robin R Ali, Rachael A Pearson
Published 2015-01-01

Dominant cone-rod dystrophy: a mouse model generated by gene targeting of the GCAP1/Guca1a gene.

by Prateek K Buch, Marija Mihelec, Phillippa Cottrill, Susan E Wilkie, Rachael A Pearson, Yanai Duran, Emma L West, Michel Michaelides, Robin R Ali, David M Hunt
Published 2011-03-01

The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice.

by Anastasios Georgiadis, Marion Tschernutter, James W B Bainbridge, Kamaljit S Balaggan, Freya Mowat, Emma L West, Peter M G Munro, Adrian J Thrasher, Karl Matter, Maria S Balda, Robin R Ali
Published 2010-12-01

Use of bioreactors for culturing human retinal organoids improves photoreceptor yields

by Patrick Ovando-Roche, Emma L. West, Matthew J. Branch, Robert D. Sampson, Milan Fernando, Peter Munro, Anastasios Georgiadis, Matteo Rizzi, Magdalena Kloc, Arifa Naeem, Joana Ribeiro, Alexander J. Smith, Anai Gonzalez-Cordero, Robin R. Ali
Published 2018-06-01

Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration

by Kamil Kruczek, Anai Gonzalez-Cordero, Debbie Goh, Arifa Naeem, Mindaugas Jonikas, Samuel J.I. Blackford, Magdalena Kloc, Yanai Duran, Anastasios Georgiadis, Robert D. Sampson, Ryea N. Maswood, Alexander J. Smith, Sarah Decembrini, Yvan Arsenijevic, Jane C. Sowden, Rachael A. Pearson, Emma L. West, Robin R. Ali
Published 2017-06-01

Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors

by Joana Ribeiro, Christopher A. Procyk, Emma L. West, Michelle O’Hara-Wright, Monica F. Martins, Majid Moshtagh Khorasani, Aura Hare, Mark Basche, Milan Fernando, Debbie Goh, Neeraj Jumbo, Matteo Rizzi, Kate Powell, Menahil Tariq, Michel Michaelides, James W.B. Bainbridge, Alexander J. Smith, Rachael A. Pearson, Anai Gonzalez-Cordero, Robin R. Ali
Published 2021-04-01

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors

by Anai Gonzalez-Cordero, Kamil Kruczek, Arifa Naeem, Milan Fernando, Magdalena Kloc, Joana Ribeiro, Debbie Goh, Yanai Duran, Samuel J.I. Blackford, Laura Abelleira-Hervas, Robert D. Sampson, Ian O. Shum, Matthew J. Branch, Peter J. Gardner, Jane C. Sowden, James W.B. Bainbridge, Alexander J. Smith, Emma L. West, Rachael A. Pearson, Robin R. Ali
Published 2017-09-01