Severe offtarget effects following intravenous delivery of AAV9-MECP2 in a female mouse model of Rett syndrome

by Valerie Matagne, Emilie Borloz, Yann Ehinger, Lydia Saidi, Laurent Villard, Jean-Christophe Roux
Published 2021-02-01

Analysis of Astroglial Secretomic Profile in the Mecp2-Deficient Male Mouse Model of Rett Syndrome

by Yann Ehinger, Valerie Matagne, Valérie Cunin, Emilie Borloz, Michel Seve, Sandrine Bourgoin-Voillard, Ana Borges-Correia, Laurent Villard, Jean-Christophe Roux
Published 2021-04-01

Ultrasound-Mediated Blood-Brain Barrier Opening Improves Whole Brain Gene Delivery in Mice

by Marie-Solenne Felix, Emilie Borloz, Khaled Metwally, Ambre Dauba, Benoit Larrat, Valerie Matagne, Yann Ehinger, Laurent Villard, Anthony Novell, Serge Mensah, Jean-Christophe Roux
Published 2021-08-01

Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice

by Yann Ehinger, Julie Bruyère, Nicolas Panayotis, Yah‐Se Abada, Emilie Borloz, Valérie Matagne, Chiara Scaramuzzino, Hélène Vitet, Benoit Delatour, Lydia Saidi, Laurent Villard, Frédéric Saudou, Jean‐Christophe Roux
Published 2020-02-01