The ALS-related σ1R E102Q Mutant Eludes Ligand Control and Exhibits Anomalous Response to Calcium

by María Rodríguez-Muñoz, Elsa Cortés-Montero, Javier Garzón-Niño, Pilar Sánchez-Blázquez
Published 2020-10-01

Ligands Exert Biased Activity to Regulate Sigma 1 Receptor Interactions With Cationic TRPA1, TRPV1, and TRPM8 Channels

by Elsa Cortés-Montero, Pilar Sánchez-Blázquez, Yara Onetti, Manuel Merlos, Javier Garzón
Published 2019-06-01

Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor

by María Rodríguez-Muñoz, Yara Onetti, Elsa Cortés-Montero, Javier Garzón, Pilar Sánchez-Blázquez
Published 2018-09-01

The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception

by Pilar Sánchez-Blázquez, Elsa Cortés-Montero, María Rodríguez-Muñoz, Manuel Merlos, Javier Garzón-Niño
Published 2020-11-01

Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue

by Elsa Cortés-Montero, María Rodríguez-Muñoz, María del Carmen Ruiz-Cantero, Enrique José Cobos, Pilar Sánchez-Blázquez, Javier Garzón-Niño
Published 2021-12-01