Generating conditional gene knockouts in Plasmodium – a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9

by Ellen Knuepfer, Marta Napiorkowska, Christiaan van Ooij, Anthony A. Holder
Published 2017-06-01

Genetic disruption of Plasmodium falciparum Merozoite surface antigen 180 (PfMSA180) suggests an essential role during parasite egress from erythrocytes

by Vanndita Bahl, Kritika Chaddha, Syed Yusuf Mian, Anthony A. Holder, Ellen Knuepfer, Deepak Gaur
Published 2021-09-01

The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake

by Emma S Sherling, Ellen Knuepfer, Joseph A Brzostowski, Louis H Miller, Michael J Blackman, Christiaan van Ooij
Published 2017-03-01

Subcellular location, phosphorylation and assembly into the motor complex of GAP45 during Plasmodium falciparum schizont development.

by Mohd A Mohd Ridzuan, Robert W Moon, Ellen Knuepfer, Sally Black, Anthony A Holder, Judith L Green
Published 2012-01-01

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.

by Parichat Prommana, Chairat Uthaipibull, Chayaphat Wongsombat, Sumalee Kamchonwongpaisan, Yongyuth Yuthavong, Ellen Knuepfer, Anthony A Holder, Philip J Shaw
Published 2013-01-01

The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion.

by Emma S Sherling, Abigail J Perrin, Ellen Knuepfer, Matthew R G Russell, Lucy M Collinson, Louis H Miller, Michael J Blackman
Published 2019-09-01

Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.

by Solabomi A Ogun, Rita Tewari, Thomas D Otto, Steven A Howell, Ellen Knuepfer, Deirdre A Cunningham, Zhengyao Xu, Arnab Pain, Anthony A Holder
Published 2011-02-01

Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranes.

by Carinne Ndjembo Ezougou, Fathia Ben-Rached, David K Moss, Jing-Wen Lin, Sally Black, Ellen Knuepfer, Judith L Green, Shahid M Khan, Amitabha Mukhopadhyay, Chris J Janse, Isabelle Coppens, Hélène Yera, Anthony A Holder, Gordon Langsley
Published 2014-01-01

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.

by Ellen Knuepfer, Katherine E Wright, Surendra Kumar Prajapati, Thomas A Rawlinson, Franziska Mohring, Marion Koch, Oliver R Lyth, Steven A Howell, Elizabeth Villasis, Ambrosius P Snijders, Robert W Moon, Simon J Draper, Anna Rosanas-Urgell, Matthew K Higgins, Jake Baum, Anthony A Holder
Published 2019-06-01

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.

by Alfred Amambua-Ngwa, Kevin K A Tetteh, Magnus Manske, Natalia Gomez-Escobar, Lindsay B Stewart, M Elizabeth Deerhake, Ian H Cheeseman, Christopher I Newbold, Anthony A Holder, Ellen Knuepfer, Omar Janha, Muminatou Jallow, Susana Campino, Bronwyn Macinnis, Dominic P Kwiatkowski, David J Conway
Published 2012-01-01