Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates.

by Jeff L Ellsworth, Jacinthe Gingras, Laura J Smith, Hillard Rubin, Tania A Seabrook, Kruti Patel, Nicole Zapata, Kevin Olivieri, Michael O'Callaghan, Elizabeth Chlipala, Pablo Morales, Albert Seymour
Published 2019-01-01