A 3D brain unit model to further improve prediction of local drug distribution within the brain.

by Esmée Vendel, Vivi Rottschäfer, Elizabeth C M de Lange
Published 2020-01-01

Imaging Techniques in Alzheimer’s Disease: A Review of Applications in Early Diagnosis and Longitudinal Monitoring

by Wieke M. van Oostveen, Elizabeth C. M. de Lange
Published 2021-02-01

The need for mathematical modelling of spatial drug distribution within the brain

by Esmée Vendel, Vivi Rottschäfer, Elizabeth C. M. de Lange
Published 2019-05-01

Impact of CNS Diseases on Drug Delivery to Brain Extracellular and Intracellular Target Sites in Human: A “WHAT-IF” Simulation Study

by Mohammed A. A. Saleh, Elizabeth C. M. de Lange
Published 2021-01-01

Revisiting atenolol as a low passive permeability marker

by Xiaomei Chen, Tim Slättengren, Elizabeth C. M. de Lange, David E. Smith, Margareta Hammarlund-Udenaes
Published 2017-10-01

Summary data of potency and parameter information from semi-mechanistic PKPD modeling of prolactin release following administration of the dopamine D2 receptor antagonists risperid...

by Amit Taneja, An Vermeulen, Dymphy R.H. Huntjens, Meindert Danhof, Elizabeth C.M. De Lange, Johannes H. Proost
Published 2016-09-01

Utility of Animal Models to Understand Human Alzheimer’s Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals

by Tian Qin, Samantha Prins, Geert Jan Groeneveld, Gerard Van Westen, Helga E. de Vries, Yin Cheong Wong, Luc J.M. Bischoff, Elizabeth C.M. de Lange
Published 2020-04-01

A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy

by Ilze Bot, Natalia V. Ortiz Zacarías, Wilhelmus E. A. de Witte, Henk de Vries, Peter J. van Santbrink, Daniël van der Velden, Mara J. Kröner, Dirk-Jan van der Berg, Dean Stamos, Elizabeth C. M. de Lange, Johan Kuiper, Adriaan P. IJzerman, Laura H. Heitman
Published 2017-03-01