Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome.

by Fiorenza Stagni, Jacopo Magistretti, Sandra Guidi, Elisabetta Ciani, Chiara Mangano, Laura Calzà, Renata Bartesaghi
Published 2013-01-01

APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome

by Stefania Trazzi, Claudia Fuchs, Marianna De Franceschi, Valentina Maria Mitrugno, Renata Bartesaghi, Elisabetta Ciani
Published 2014-07-01

Corrigendum to “APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome” [Neurobiology of Disease 67 (2014) 24–36]

by Stefania Trazzi, Claudia Fuchs, Marianna De Franceschi, Valentina Maria Mitrugno, Renata Bartesaghi, Elisabetta Ciani
Published 2020-05-01

Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder

by Claudia Fuchs, Roberto Rimondini, Rocchina Viggiano, Stefania Trazzi, Marianna De Franceschi, Renata Bartesaghi, Elisabetta Ciani
Published 2015-10-01

Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome

by Andrea Giacomini, Fiorenza Stagni, Stefania Trazzi, Sandra Guidi, Marco Emili, Elizabeth Brigham, Elisabetta Ciani, Renata Bartesaghi
Published 2015-10-01

Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder

by Giuseppe Galvani, Nicola Mottolese, Laura Gennaccaro, Manuela Loi, Giorgio Medici, Marianna Tassinari, Claudia Fuchs, Elisabetta Ciani, Stefania Trazzi
Published 2021-07-01

Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice

by Fiorenza Stagni, Andrea Giacomini, Sandra Guidi, Elisabetta Ciani, Elena Ragazzi, Mirco Filonzi, Rosaria De Iasio, Roberto Rimondini, Renata Bartesaghi
Published 2015-02-01

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

by Claudia Fuchs, Stefania Trazzi, Roberta Torricella, Rocchina Viggiano, Marianna De Franceschi, Elena Amendola, Cornelius Gross, Laura Calzà, Renata Bartesaghi, Elisabetta Ciani
Published 2014-10-01

Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome

by Fiorenza Stagni, Alessandra Raspanti, Andrea Giacomini, Sandra Guidi, Marco Emili, Elisabetta Ciani, Alessandro Giuliani, Andrea Bighinati, Laura Calzà, Jacopo Magistretti, Renata Bartesaghi
Published 2017-07-01

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder

by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani
Published 2018-01-01

Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of <i>CDKL5</i> Deficiency Disorder

by Manuela Loi, Laura Gennaccaro, Claudia Fuchs, Stefania Trazzi, Giorgio Medici, Giuseppe Galvani, Nicola Mottolese, Marianna Tassinari, Roberto Rimondini Giorgini, Andrea Milelli, Elisabetta Ciani
Published 2021-05-01

Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist

by Elisa Ren, Vincenzo Roncacé, Stefania Trazzi, Claudia Fuchs, Giorgio Medici, Laura Gennaccaro, Manuela Loi, Giuseppe Galvani, Keqiang Ye, Roberto Rimondini, Giorgio Aicardi, Giorgio Aicardi, Elisabetta Ciani
Published 2019-04-01

Mapping pathological phenotypes in a mouse model of CDKL5 disorder.

by Elena Amendola, Yang Zhan, Camilla Mattucci, Enrico Castroflorio, Eleonora Calcagno, Claudia Fuchs, Giuseppina Lonetti, Davide Silingardi, Alexei L Vyssotski, Dominika Farley, Elisabetta Ciani, Tommaso Pizzorusso, Maurizio Giustetto, Cornelius T Gross
Published 2014-01-01

A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder

by Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali, Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani
Published 2021-06-01