Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration

by Rachel E. James, Renee Schalks, Eleanor Browne, Ioanna Eleftheriadou, Carmen Picon Munoz, Nicholas D. Mazarakis, Richard Reynolds
Published 2020-05-01

Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier.

by Patricia Gallego-Delgado, Rachel James, Eleanor Browne, Joanna Meng, Swetha Umashankar, Li Tan, Carmen Picon, Nicholas D Mazarakis, A Aldo Faisal, Owain W Howell, Richard Reynolds
Published 2020-12-01