Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay

by Nirmala Sirisena, Kajal Biswas, Teresa Sullivan, Stacey Stauffer, Linda Cleveland, Eileen Southon, Vajira H. W. Dissanayake, Shyam K. Sharan
Published 2020-05-01

A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays

by Kajal Biswas, Gary B. Lipton, Stacey Stauffer, Teresa Sullivan, Linda Cleveland, Eileen Southon, Susan Reid, Valentin Magidson, Edwin S. Iversen, Shyam K. Sharan
Published 2020-12-01

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).

by Yassin Mahdi, Xue-Ming Xu, Bradley A Carlson, Noelia Fradejas, Paul Günter, Doreen Braun, Eileen Southon, Lino Tessarollo, Dolph L Hatfield, Ulrich Schweizer
Published 2015-01-01

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.

by Suzanne A Hartford, Rajanikant Chittela, Xia Ding, Aradhana Vyas, Betty Martin, Sandra Burkett, Diana C Haines, Eileen Southon, Lino Tessarollo, Shyam K Sharan
Published 2016-08-01

Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.

by Joseph Landry, Alexei A Sharov, Yulan Piao, Lioudmila V Sharova, Hua Xiao, Eileen Southon, Jennifer Matta, Lino Tessarollo, Ying E Zhang, Minoru S H Ko, Michael R Kuehn, Terry P Yamaguchi, Carl Wu
Published 2008-10-01

A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing

by Kajal Biswas, Martin Couillard, Luca Cavallone, Sandra Burkett, Stacey Stauffer, Betty K. Martin, Eileen Southon, Susan Reid, Teri M. Plona, Ryan N. Baugher, Stephanie D. Mellott, Kristen M. Pike, Mary E. Albaugh, Chelsea Maedler-Kron, Nancy Hamel, Lino Tessarollo, Victoria Marcus, William D. Foulkes, Shyam K. Sharan
Published 2021-09-01