The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy

by Anastasia Mpakali, Efstratios Stratikos
Published 2021-01-01

The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases

by Athanasios Papakyriakou, Athanasios Papakyriakou, Efstratios Stratikos
Published 2017-08-01

Thermodynamic destabilization and aggregation propensity as the mechanism behind the association of apoE3 mutants and lipoprotein glomerulopathy

by Maria Katsarou, Efstratios Stratikos, Angeliki Chroni
Published 2018-12-01

Discovery of Selective Inhibitor Leads by Targeting an Allosteric Site in Insulin-Regulated Aminopeptidase

by Ioannis Temponeras, Lykourgos Chiniadis, Athanasios Papakyriakou, Efstratios Stratikos
Published 2021-06-01

Editorial: Physiological, Pathological Roles and Pharmacology of Insulin Regulated Aminopeptidase

by Siew Yeen Chai, Hugo Gutiérrez-de-Terán, Efstratios Stratikos
Published 2021-04-01

Biophysical analysis of apolipoprotein E3 variants linked with development of type III hyperlipoproteinemia.

by Dimitra Georgiadou, Angeliki Chroni, Alexander Vezeridis, Vassilis I Zannis, Efstratios Stratikos
Published 2011-01-01

Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

by Zachary Maben, Richa Arya, Dimitris Georgiadis, Efstratios Stratikos, Lawrence J. Stern
Published 2021-09-01

The Pivotal Role of Protein Phosphorylation in the Control of Yeast Central Metabolism

by Panayotis Vlastaridis, Athanasios Papakyriakou, Anargyros Chaliotis, Efstratios Stratikos, Stephen G. Oliver, Grigorios D. Amoutzias
Published 2017-04-01

Thermodynamic and structural destabilization of apoE3 by hereditary mutations associated with the development of lipoprotein glomerulopathy[S]

by Dimitra Georgiadou, Kostas Stamatakis, Eleni K. Efthimiadou, George Kordas, Donald Gantz, Angeliki Chroni, Efstratios Stratikos
Published 2013-01-01

The internal sequence of the peptide-substrate determines its N-terminus trimming by ERAP1.

by Irini Evnouchidou, Frank Momburg, Athanasios Papakyriakou, Angeliki Chroni, Leondios Leondiadis, Shih-Chung Chang, Alfred L Goldberg, Efstratios Stratikos
Published 2008-01-01

Significance of the hydrophobic residues 225–230 of apoA-I for the biogenesis of HDL1[S]

by Panagiotis Fotakis, Ioanna Tiniakou, Andreas K. Kateifides, Christina Gkolfinopoulou, Angeliki Chroni, Efstratios Stratikos, Vassilis I. Zannis, Dimitris Kardassis
Published 2013-12-01

The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I

by George Mavridis, Anastasia Mpakali, Jerome Zoidakis, Manousos Makridakis, Antonia Vlahou, Eleni Kaloumenou, Angeliki Ziotopoulou, Dimitris Georgiadis, Athanasios Papakyriakou, Efstratios Stratikos
Published 2021-08-01

ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT[S]

by Adelina Duka, Panagiotis Fotakis, Dimitra Georgiadou, Andreas Kateifides, Kalliopi Tzavlaki, Leonard von Eckardstein, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
Published 2013-01-01

The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia

by Kimberly Seamon, Lesia O. Kurlak, Michelle Warthan, Efstratios Stratikos, Jerome F. Strauss, Hiten D. Mistry, Eun D. Lee, Eun D. Lee
Published 2020-03-01

Role of the hydrophobic and charged residues in the 218–226 region of apoA-I in the biogenesis of HDL1[S]

by Panagiotis Fotakis, Andreas K. Kateifides, Christina Gkolfinopoulou, Dimitra Georgiadou, Melissa Beck, Katharina Gründler, Angeliki Chroni, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
Published 2013-12-01

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

by Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Céline Schmitt, Sarah Alavi, Isabelle Florent, Anthony Addlagatta, Efstratios Stratikos, Céline Tarnus, Sébastien Albrecht
Published 2018-10-01

ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29

by Wouter J. Venema, Wouter J. Venema, Sanne Hiddingh, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander, Anneke I. den Hollander, Efstratios Stratikos, Siranush Sarkizova, Siranush Sarkizova, Lars T. van der Veken, George M. C. Janssen, Peter A. van Veelen, Jonas J. W. Kuiper, Jonas J. W. Kuiper
Published 2021-02-01