Structural basis for tuning activity and membrane specificity of bacterial cytolysins

by Nita R. Shah, Tomas B. Voisin, Edward S. Parsons, Courtney M. Boyd, Bart W. Hoogenboom, Doryen Bubeck
Published 2020-11-01

Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7.

by Dennis J Doorduijn, Bart W Bardoel, Dani A C Heesterbeek, Maartje Ruyken, Georgina Benn, Edward S Parsons, Bart W Hoogenboom, Suzan H M Rooijakkers
Published 2020-06-01

Single-molecule kinetics of pore assembly by the membrane attack complex

by Edward S. Parsons, George J. Stanley, Alice L. B. Pyne, Adrian W. Hodel, Adrian P. Nievergelt, Anaïs Menny, Alexander R. Yon, Ashlea Rowley, Ralf P. Richter, Georg E. Fantner, Doryen Bubeck, Bart W. Hoogenboom
Published 2019-05-01

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

by Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A. Spicer, Ruby H. P. Law, Adrian W. Hodel, Edward S. Parsons, Susan M. Ekkel, Paul J. Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I. Bird, Bart W. Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A. Dunstone, James C. Whisstock
Published 2019-09-01