The NS4A Cofactor Dependent Enhancement of HCV NS3 Protease Activity Correlates with a 4D Geometrical Measure of the Catalytic Triad Region.

by Hamzah A Hamad, Jeremy Thurston, Thomas Teague, Edward Ackad, Mohammad S Yousef
Published 2016-01-01

Comparative molecular dynamics simulation of Hepatitis C Virus NS3/4A protease (Genotypes 1b, 3a and 4b) predicts conformational instability of the catalytic triad in drug resistan...

by Mitchell Kramer, Daniel Halleran, Moazur Rahman, Mazhar Iqbal, Muhammad Ikram Anwar, Salwa Sabet, Edward Ackad, Mohammad S Yousef
Published 2014-01-01