Autoimmune Diseases in the Bioinformatics Paradigm

by Quan-Zhen Li, Edward K. Wakeland
Published 2015-08-01

T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells

by Aakanksha Jain, Ran Song, Edward K. Wakeland, Chandrashekhar Pasare
Published 2018-08-01

Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus.

by Ruth Levitz, Yajing Gao, Igor Dozmorov, Ran Song, Edward K Wakeland, Jeffrey S Kahn
Published 2017-01-01

Genomic Heterogeneity of Methicillin Resistant Staphylococcus aureus Associated with Variation in Severity of Illness among Children with Acute Hematogenous Osteomyelitis.

by Claudia Gaviria-Agudelo, Chukwuemika Aroh, Naureen Tareen, Edward K Wakeland, MinSoo Kim, Lawson A Copley
Published 2015-01-01

The impact of Staphylococcus aureus genomic variation on clinical phenotype of children with acute hematogenous osteomyelitis

by Angela Collins, Edward K. Wakeland, Prithvi Raj, Min S. Kim, Jiwoong Kim, Naureen G. Tareen, Lawson A.B. Copley
Published 2018-06-01

Influence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical Artery Smooth Muscle Cells and Vein Endothelial Cells

by Yajuan Li, Hai Wang, Bin Yang, Jichen Yang, Xiuyan Ruan, Yadong Yang, Edward K. Wakeland, Quanzhen Li, Xiangdong Fang
Published 2012-01-01

Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.

by Rui-Jun Su, Yadong Yang, Amanda Neises, Kimberly J Payne, Jasmin Wang, Kasthuribai Viswanathan, Edward K Wakeland, Xiangdong Fang, Xiao-Bing Zhang
Published 2013-01-01

Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements.

by Lingxiang Zhu, Zhongqiang Yan, Zhaojun Zhang, Qiming Zhou, Jinchun Zhou, Edward K Wakeland, Xiangdong Fang, Zhenyu Xuan, Dingxia Shen, Quan-Zhen Li
Published 2013-01-01

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

by Ran Song, Yajing Gao, Igor Dozmorov, Venkat Malladi, Irene Saha, Margaret M. McDaniel, Sreeja Parameswaran, Chaoying Liang, Carlos Arana, Bo Zhang, Benjamin Wakeland, Jinchun Zhou, Matthew T. Weirauch, Leah C. Kottyan, Edward K. Wakeland, Chandrashekhar Pasare
Published 2021-03-01

Association between body mass index, dosing strategy, and efficacy of immune checkpoint inhibitors

by Yang Xie, Vinita Popat, Shaheen Khan, Saad A Khan, Edward K Wakeland, Quan-Zhen Li, Murtaza Ahmed, Mitchell S von Itzstein, Thomas Sheffield, Farjana Fattah, Jason Y Park, Jessica M Saltarski, Yvonne Gloria-McCutchen, David Hsiehchen, Jared Ostmeyer, Nazima Sultana
Published 2021-06-01

sncRNA-1 Is a Small Noncoding RNA Produced by Mycobacterium tuberculosis in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis

by Fatma S. Coskun, Shashikant Srivastava, Prithvi Raj, Igor Dozmorov, Serkan Belkaya, Smriti Mehra, Nadia A. Golden, Allison N. Bucsan, Moti L. Chapagain, Edward K. Wakeland, Deepak Kaushal, Deepak Kaushal, Tawanda Gumbo, Nicolai S. C. van Oers, Nicolai S. C. van Oers, Nicolai S. C. van Oers
Published 2020-07-01

Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells

by Satoko Arai, Natsumi Maehara, Yoshihiro Iwamura, Shin-ichiro Honda, Katsuhiko Nakashima, Toshihiro Kai, Masato Ogishi, Kumiko Morita, Jun Kurokawa, Mayumi Mori, Yuji Motoi, Kensuke Miyake, Nobuyuki Matsuhashi, Ken-ichi Yamamura, Osamu Ohara, Akira Shibuya, Edward K. Wakeland, Quan-Zhen Li, Toru Miyazaki
Published 2013-04-01

SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature.

by Amy M Becker, Kathryn H Dao, Bobby Kwanghoon Han, Roger Kornu, Shuchi Lakhanpal, Angela B Mobley, Quan-Zhen Li, Yun Lian, Tianfu Wu, Andreas M Reimold, Nancy J Olsen, David R Karp, Fatema Z Chowdhury, J David Farrar, Anne B Satterthwaite, Chandra Mohan, Peter E Lipsky, Edward K Wakeland, Laurie S Davis
Published 2013-01-01

Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus

by Prithvi Raj, Ran Song, Honglin Zhu, Linley Riediger, Dong-Jae Jun, Chaoying Liang, Carlos Arana, Bo Zhang, Yajing Gao, Benjamin E. Wakeland, Igor Dozmorov, Jinchun Zhou, Jennifer A. Kelly, Bernard R. Lauwerys, Joel M. Guthridge, Nancy J. Olsen, Swapan K. Nath, Chandrashekhar Pasare, Nicolai van Oers, Gary Gilkeson, Betty P. Tsao, Patrick M. Gaffney, Peter K. Gregersen, Judith A. James, Xiaoxia Zuo, David R. Karp, Quan-Zhen Li, Edward K. Wakeland
Published 2020-11-01

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

by Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland
Published 2016-02-01

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians.

by Julio E Molineros, Loren L Looger, Kwangwoo Kim, Yukinori Okada, Chikashi Terao, Celi Sun, Xu-Jie Zhou, Prithvi Raj, Yuta Kochi, Akari Suzuki, Shuji Akizuki, Shuichiro Nakabo, So-Young Bang, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Yong-Beom Park, Jung-Yoon Choe, Seung-Cheol Shim, Shin-Seok Lee, Xiaoxia Zuo, Kazuhiko Yamamoto, Quan-Zhen Li, Nan Shen, Lauren L Porter, John B Harley, Kek Heng Chua, Hong Zhang, Edward K Wakeland, Betty P Tsao, Sang-Cheol Bae, Swapan K Nath
Published 2019-04-01

Transancestral mapping and genetic load in systemic lupus erythematosus

by Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Published 2017-07-01